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Everything about PTPRG
Protein-coding gene in the species Homo sapiens
Receptor-type tyrosine-protein phosphatase gamma is an enzyme that in humans is encoded by the PTPRG gene. Wikipedia ā
š§ Start here: a 6-step reading path
- Read the overview: PTPRGA 5-minute orientation
- Skim a recent paper: Single-cell and spatial transcriptomics reveals that PTPRG activates the m6A methyltransferase VIRMA to block mitophagy-mediated neuronal death in Alzheimerās diseaseInfluential work since 2022
- Read the landmark paper: Epigenetic Profiling of Cutaneous T-Cell Lymphoma: Promoter Hypermethylation of Multiple Tumor Suppressor Genes Including BCL7a, PTPRG, and p73Cited 199 times
- Go sideways: PTPRTA closely related topic
- Go sideways: PTPRKA closely related topic
š Definitions
No dictionary entry for this exact phrase.
šļø The subject at a glance
No outline available.
š Landmark papers (most cited)
Epigenetic Profiling of Cutaneous T-Cell Lymphoma: Promoter Hypermethylation of Multiple Tumor Suppressor Genes Including BCL7a, PTPRG, and p73
The protein tyrosine phosphatases PTPRZ and PTPRG bind to distinct members of the contactin family of neural recognition molecules
Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimerās disease with OSBPL6, PTPRG, and PDCL3
Long noncoding RNA PTPRGāAS1 acts as a microRNAā194ā3p sponge to regulate radiosensitivity and metastasis of nasopharyngeal carcinoma cells via PRC1
PTPRG suppresses tumor growth and invasion via inhibition of Akt signaling in nasopharyngeal carcinoma
Contactin 4, -5 and -6 differentially regulate neuritogenesis while they display identical PTPRG binding sites
Protein Tyrosine Phosphatase Receptor Type G (PTPRG) Controls Fibroblast Growth Factor Receptor (FGFR) 1 Activity and Influences Sensitivity to FGFR Kinase Inhibitors
The tumour suppressor OPCML promotes AXL inactivation by the phosphatase PTPRG in ovarian cancer
š Influential since 2022
Single-cell and spatial transcriptomics reveals that PTPRG activates the m6A methyltransferase VIRMA to block mitophagy-mediated neuronal death in Alzheimerās disease
A Comprehensive Review of Receptor-Type Tyrosine-Protein Phosphatase Gamma (PTPRG) Role in Health and Non-Neoplastic Disease
POU2F2-mediated Upregulation of lncRNA PTPRG-AS1 Inhibits Ferroptosis in Breast Cancer Via miR-376c-3p/SLC7A11 Axis
LncRNA PTPRGāAS1 facilitates glycolysis and stemness properties of esophageal squamous cell carcinoma cells through miRā599/PDK1 axis
Long non-coding RNA PTPRG-AS1/microRNA-124-3p regulates radiosensitivity of nasopharyngeal carcinoma via the LIM Homeobox 2-dependent Notch pathway through competitive endogenous RNA mechanism
š Books worth reading
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š Related topics
- PTPRT Receptor-type tyrosine-protein phosphatase T is an enzyme that in humans is encoded by the PTPRT gene. PTPRT is also known as PTPrho, PTPĻ and human acceleratedā¦
- PTPRK Receptor-type tyrosine-protein phosphatase kappa is an enzyme that in humans is encoded by the PTPRK gene. PTPRK is also known as PTPkappa and PTPĪŗ. Theā¦
- PTPRD Receptor-type tyrosine-protein phosphatase delta is an enzyme that, in humans, is encoded by the PTPRD gene. The protein encoded by this gene is a memberā¦
- PTPRF Receptor-type tyrosine-protein phosphatase F is an enzyme that, in humans, is encoded by the PTPRF gene. The protein encoded by this gene is a member ofā¦
- PTPRH Receptor-type tyrosine-protein phosphatase H is an enzyme that in humans is encoded by the PTPRH gene. The protein encoded by this gene is a member ofā¦
- PTPN18 Tyrosine-protein phosphatase non-receptor type 18 is an enzyme that in humans is encoded by the PTPN18 gene. The protein encoded by this gene is a memberā¦
- PTPRB Receptor-type tyrosine-protein phosphatase beta or VE-PTP is an enzyme specifically expressed in endothelial cells that in humans is encoded by the PTPRBā¦
- PTPRU Receptor-type tyrosine-protein phosphatase PCP-2 (also known as PTP-pi, PTP lambda, hPTP-J, PTPRO and PTP psi), is an enzyme that in humans is encodedā¦