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Everything about PTPRB
Protein-coding gene in the species Homo sapiens
Receptor-type tyrosine-protein phosphatase beta or VE-PTP is an enzyme specifically expressed in endothelial cells that in humans is encoded by the PTPRB gene. Wikipedia →
🧭 Start here: a 6-step reading path
- Read the overview: PTPRBA 5-minute orientation
- Skim a recent paper: Rare genetic variation in PTPRB is associated with central serous chorioretinopathy, varicose veins and glaucomaInfluential work since 2022
- Read the landmark paper: Recurrent PTPRB and PLCG1 mutations in angiosarcomaCited 301 times
- Go sideways: VE-cadherinA closely related topic
- Go sideways: PTPRMA closely related topic
📖 Definitions
No dictionary entry for this exact phrase.
🗂️ The subject at a glance
🏆 Landmark papers (most cited)
Recurrent PTPRB and PLCG1 mutations in angiosarcoma
RETRACTED ARTICLE: miR-665 promotes hepatocellular carcinoma cell migration, invasion, and proliferation by decreasing Hippo signaling through targeting PTPRB
miR-624-5p promoted tumorigenesis and metastasis by suppressing hippo signaling through targeting PTPRB in osteosarcoma cells
Targeting the vascular-specific phosphatase PTPRB protects against retinal ganglion cell loss in a pre-clinical model of glaucoma
Forsythoside A regulates pulmonary fibrosis by inhibiting endothelial-to-mesenchymal transition and lung fibroblast proliferation via the PTPRB signaling
PTPRB promotes metastasis of colorectal carcinoma via inducing epithelial-mesenchymal transition
PSMD11, PTPRM and PTPRB as novel biomarkers of pancreatic cancer progression
Protein tyrosine phosphatase PTPRB regulates Src phosphorylation and tumour progression in NSCLC
🆕 Influential since 2022
Rare genetic variation in PTPRB is associated with central serous chorioretinopathy, varicose veins and glaucoma
Exosomal SPRY4 from adipogenic BMSCs impairs angiogenesis via the PTPRB/TIE2/PI3K axis in Steroid-induced osteonecrosis of the femoral head
Novel rare mutation in a conserved site of PTPRB causes human hypoplastic left heart syndrome
The variants in PTPRB, TRAF3IP3, and DISC1 genes were associated with Graves’ disease in the Chinese population
Investigation of a Glioblastoma Risk-Associated SNP of the PTPRB Gene in Familial Glioblastoma
📚 Books worth reading
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🔗 Related topics
- VE-cadherin Cadherin-5, or VE-cadherin (vascular endothelial cadherin), also known as CD144 (Cluster of Differentiation 144), is a type of cadherin. It is encoded…
- PTPRM Receptor-type tyrosine-protein phosphatase mu is an enzyme that in humans is encoded by the PTPRM gene. The protein encoded by this gene is a member of…
- Kinase insert domain receptor Kinase insert domain receptor (KDR, a type IV receptor tyrosine kinase) also known as vascular endothelial growth factor receptor 2 (VEGFR-2) is a VEGF…
- Vascular endothelial growth factor A Vascular endothelial growth factor A (VEGF-A) is a protein that in humans is encoded by the VEGFA gene. The chemical formula is C3914H6252N1212O1278S52…
- PTPRT Receptor-type tyrosine-protein phosphatase T is an enzyme that in humans is encoded by the PTPRT gene. PTPRT is also known as PTPrho, PTPρ and human accelerated…
- PTPN14 Tyrosine-protein phosphatase non-receptor type 14 is an enzyme that in humans is encoded by the PTPN14 gene. It is composes of a PTP (protein tyrosine…
- Receptor tyrosine kinase Receptor tyrosine kinases (RTKs) are the high-affinity cell surface receptors for many polypeptide growth factors, cytokines, and hormones. Of the 90 unique…
- Vascular endothelial growth factor Vascular endothelial growth factor (VEGF, /vɛdʒˈɛf/), originally known as vascular permeability factor (VPF), is a signal protein produced by many cells…