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Everything about PTPRT
Protein-coding gene in the species Homo sapiens
Receptor-type tyrosine-protein phosphatase T is an enzyme that in humans is encoded by the PTPRT gene. Wikipedia →
🧭 Start here: a 6-step reading path
- Read the overview: PTPRTA 5-minute orientation
- Skim a recent paper: PTPRT loss enhances anti–PD-1 therapy efficacy by regulation of STING pathway in non–small cell lung cancerInfluential work since 2022
- Read the landmark paper: Protein tyrosine phosphatase PTPRT as a regulator of synaptic formation and neuronal developmentCited 52 times
- Go sideways: PTPRUA closely related topic
- Go sideways: PTPRMA closely related topic
📖 Definitions
No dictionary entry for this exact phrase.
🏆 Landmark papers (most cited)
Protein tyrosine phosphatase PTPRT as a regulator of synaptic formation and neuronal development
miR-532-3p promotes hepatocellular carcinoma progression by targeting PTPRT
Frequent promoter hypermethylation of PTPRT increases STAT3 activation and sensitivity to STAT3 inhibition in head and neck cancer
Tumor-Derived Extracellular Mutations of PTPRT/PTPρ Are Defective in Cell Adhesion
PTPRT and PTPRD Deleterious Mutations and Deletion Predict Bevacizumab Resistance in Metastatic Colorectal Cancer Patients
Regulation of paxillin-p130-PI3K-AKT signaling axis by Src and PTPRT impacts colon tumorigenesis
Hepatitis B virus X protein mutant HBxΔ127 promotes proliferation of hepatoma cells through up-regulating miR-215 targeting PTPRT
Association of PTPRT mutations with immune checkpoint inhibitors response and outcome in melanoma and non‐small cell lung cancer
🆕 Influential since 2022
PTPRT loss enhances anti–PD-1 therapy efficacy by regulation of STING pathway in non–small cell lung cancer
PTPRD/PTPRT mutation as a predictive biomarker of immune checkpoint inhibitors across multiple cancer types
LINC01534/miR-135b-5p/PTPRT axis regulates inflammatory response in loosening total hip replacement via modulating NF-κB signaling pathway
Association of PTPRT Mutations with Cancer Metastasis in Multiple Cancer Types
ADAM10 ‐ and γ‐secretase‐dependent cleavage of the transmembrane protein PTPRT attenuates neurodegeneration in the mouse model of Alzheimer's disease
📚 Books worth reading
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🔗 Related topics
- PTPRU Receptor-type tyrosine-protein phosphatase PCP-2 (also known as PTP-pi, PTP lambda, hPTP-J, PTPRO and PTP psi), is an enzyme that in humans is encoded…
- PTPRM Receptor-type tyrosine-protein phosphatase mu is an enzyme that in humans is encoded by the PTPRM gene. The protein encoded by this gene is a member of…
- PTPRK Receptor-type tyrosine-protein phosphatase kappa is an enzyme that in humans is encoded by the PTPRK gene. PTPRK is also known as PTPkappa and PTPκ. The…
- PTPRF Receptor-type tyrosine-protein phosphatase F is an enzyme that, in humans, is encoded by the PTPRF gene. The protein encoded by this gene is a member of…
- PTPRD Receptor-type tyrosine-protein phosphatase delta is an enzyme that, in humans, is encoded by the PTPRD gene. The protein encoded by this gene is a member…
- PTPN11 Tyrosine-protein phosphatase non-receptor type 11 (PTPN11) also known as protein-tyrosine phosphatase 1D (PTP-1D), Src homology region 2 domain-containing…
- PTPN12 Tyrosine-protein phosphatase non-receptor type 12 is an enzyme that in humans is encoded by the PTPN12 gene. The protein encoded by this gene is a member…
- PTPN1 Tyrosine-protein phosphatase non-receptor type 1 also known as protein-tyrosine phosphatase 1B (PTP1B) is an enzyme that is the founding member of the…