Live briefing
Everything about Massively parallel sequencing
DNA sequencing using the concept of massively parallel processing
Massively parallel sequencing (MPS) is any of several high-throughput approaches to DNA sequencing using the concept of massively parallel processing; it is also called next-generation sequencing (NGS) or second-generation sequencing. Some of these technologies emerged between 1993 and 1998 and have been commercially available since 2005. These technologies use miniaturized and parallelized platforms for sequencing of 1 million to 43 billion short reads per instrument run. Wikipedia →
🧭 Start here: a 6-step reading path
- Read the overview: Massively parallel sequencingA 5-minute orientation
- Skim a recent paper: Massively parallel enrichment of low-frequency alleles enables duplex sequencing at low depthInfluential work since 2022
- Pick up a classic book: Statistical Atlases and Computational Models of the Heart. Imaging and Modelling ChallengesThe most-reprinted book on the subject
- Read the landmark paper: Mapping the Hallmarks of Lung Adenocarcinoma with Massively Parallel SequencingCited 1,643 times
- Go sideways: DNA sequencerA closely related topic
- Go sideways: DNA sequencingA closely related topic
📖 Definitions
No dictionary entry for this exact phrase.
🗂️ The subject at a glance
🏆 Landmark papers (most cited)
Mapping the Hallmarks of Lung Adenocarcinoma with Massively Parallel Sequencing
Development of Personalized Tumor Biomarkers Using Massively Parallel Sequencing
DNA SEQUENCING: Massively Parallel Genomics
Gene expression profiling by massively parallel sequencing
Massively parallel sequencing techniques for forensics: A review
Massively parallel sequencing and rare disease
Massively Parallel Sequencing for Genetic Diagnosis of Hearing Loss
Massively parallel sequencing
🆕 Influential since 2022
Massively parallel enrichment of low-frequency alleles enables duplex sequencing at low depth
Rapid discovery of high-affinity antibodies via massively parallel sequencing, ribosome display and affinity screening
Efficient and accurate KIR and HLA genotyping with massively parallel sequencing data
Whole Genome Amplification in Preimplantation Genetic Testing in the Era of Massively Parallel Sequencing
Massively parallel single-cell sequencing of diverse microbial populations
📚 Books worth reading
Statistical Atlases and Computational Models of the Heart. Imaging and Modelling ChallengesOscar Camara · 2012
BioinformaticsBertil Schmidt · 2010
Principles of gene manipulation and genomicsS. B. Primrose · 2006
High-throughput next generation sequencingYoung Min Kwon, Steven C. Ricke · 2011
Genomic structural variantsLars Feuk · 2012- 📕Immune homeostasisAndrew L. Snow, Michael Lenardo · 2013
RNAi and microRNA-mediated gene regulation in stem cellsBaohong Zhang, Edmund J. Stellwag · 2010
Gene regulatory networksBart Deplancke, Nele Gheldof · 2012
Ranked by number of editions on Open Library, a rough measure of how lasting a book is.
🔗 Related topics
- DNA sequencer A DNA sequencer is a scientific instrument used to automate the process of DNA sequencing. Given a DNA sample, the DNA sequencer is used to determine the…
- DNA sequencing DNA sequencing is the process of determining the nucleic acid sequence – the order of nucleotides in DNA. It includes any method or technology that is…
- Illumina dye sequencing Illumina dye sequencing is a technique used to determine the series of base pairs in DNA, also known as DNA sequencing. The reversible terminated chemistry…
- Sequencing In genetics and biochemistry, sequencing means to determine the primary structure (sometimes incorrectly called the primary sequence) of an unbranched…
- Cap analysis of gene expression Cap analysis of gene expression (CAGE) is a gene expression technique used in molecular biology to produce a snapshot of the 5′ end of the messenger RNA…
- Duplex sequencing Duplex sequencing is a library preparation and analysis method for next-generation sequencing (NGS) platforms that employs random tagging of double-stranded…
- Single-molecule real-time sequencing Single-molecule real-time (SMRT) sequencing is a parallelized single molecule DNA sequencing method. Single-molecule real-time sequencing utilizes a zero-mode…
- Sanger sequencing Sanger sequencing is a method of DNA sequencing that involves electrophoresis and is based on the random incorporation of chain-terminating dideoxynucleotides…