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Everything about DNA sequencer
Scientific instrument that automates the DNA sequencing process
A DNA sequencer is a scientific instrument used to automate the process of DNA sequencing. Given a DNA sample, the DNA sequencer is used to determine the sequence of the four bases it contains: G (guanine), C (cytosine), A (adenine), and T (thymine). Wikipedia →
🧭 Start here: a 6-step reading path
- Read the overview: DNA sequencerA 5-minute orientation
- Skim a recent paper: Nanopore-based technologies beyond DNA sequencingInfluential work since 2022
- Pick up a classic book: Gene Cloning and DNA AnalysisThe most-reprinted book on the subject
- Read the landmark paper: DNA sequencing with chain-terminating inhibitorsCited 42,649 times
- Go sideways: Massively parallel sequencingA closely related topic
- Go sideways: SOLiD sequencingA closely related topic
📖 Definitions
No dictionary entry for this exact phrase.
🗂️ The subject at a glance
🏆 Landmark papers (most cited)
DNA sequencing with chain-terminating inhibitors
The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data
Detection of specific sequences among DNA fragments separated by gel electrophoresis
Ultrafast and memory-efficient alignment of short DNA sequences to the human genome
Evolutionary trees from DNA sequences: A maximum likelihood approach
A framework for variation discovery and genotyping using next-generation DNA sequencing data
Tandem repeats finder: a program to analyze DNA sequences
DnaSP 6: DNA Sequence Polymorphism Analysis of Large Data Sets
🆕 Influential since 2022
Nanopore-based technologies beyond DNA sequencing
Drag-and-drop genome insertion of large sequences without double-strand DNA cleavage using CRISPR-directed integrases
Predicting RNA splicing from DNA sequence using Pangolin
DeepSTARR predicts enhancer activity from DNA sequence and enables the de novo design of synthetic enhancers
Predicting RNA-seq coverage from DNA sequence as a unifying model of gene regulation
📚 Books worth reading
Gene Cloning and DNA AnalysisT. A. Brown · 2001- 📕DNA systematicsS. K. Dutta · 1986
Introduction to cancer biologyRobin Hesketh · 2012- 📕DNA NanoscienceKenneth Douglas · 2016
A biologist's guide to analysis of DNA microarray dataSteen Knudsen · 2002
RNA and DNA EditingHarold C. Smith · 2007- 📕Next Generation Sequencing Data AnalysisXinkun Wang · 2016
Bacterial Integrative Mobile Genetic ElementsAdam P. Roberts, Peter Mullany · 2013
Ranked by number of editions on Open Library, a rough measure of how lasting a book is.
🔗 Related topics
- Massively parallel sequencing Massively parallel sequencing (MPS) is any of several high-throughput approaches to DNA sequencing using the concept of massively parallel processing;…
- SOLiD sequencing Sequencing by Oligonucleotide Ligation and Detection (SOLiD) is a DNA sequencing technology developed by Life Technologies and has been available since…
- DNA sequencing DNA sequencing is the process of determining the nucleic acid sequence – the order of nucleotides in DNA. It includes any method or technology that is…
- 454 Life Sciences 454 Life Sciences was a biotechnology company based in Branford, Connecticut, that specialized in high-throughput DNA sequencing. It was acquired by Roche…
- Illumina, Inc. Illumina, Inc. is an American biotechnology company, headquartered in San Diego, California. Incorporated on April 1, 1998, Illumina develops, manufactures…
- Third-generation sequencing Third-generation sequencing (also known as long-read sequencing) is a class of DNA sequencing methods that have the capability to produce substantially…
- Sequence assembly In bioinformatics, sequence assembly refers to aligning and merging fragments from a longer DNA sequence in order to reconstruct the original sequence…
- Illumina dye sequencing Illumina dye sequencing is a technique used to determine the series of base pairs in DNA, also known as DNA sequencing. The reversible terminated chemistry…