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Everything about Peptide microarray
A peptide microarray is a collection of peptides displayed on a solid surface, usually a glass or plastic chip. Peptide chips are used by scientists in biology, medicine and pharmacology to study binding properties and functionality and kinetics of protein-protein interactions in general. In basic research, peptide microarrays are often used to profile an enzyme, to map an antibody epitope or to find key residues for protein binding. Practical applications are seromarker discovery, profiling of changing humoral immune responses of individual patients during disease progression, monitoring of therapeutic interventions, patient stratification and development of diagnostic tools and vaccines. Wikipedia →
🧭 Start here: a 6-step reading path
- Read the overview: Peptide microarrayA 5-minute orientation
- Skim a recent paper: Development of a peptide microarray-based metal-enhanced fluorescence assay for ultrasensitive detection of multiple matrix metalloproteinase activities by using a gold nanorod-polymer substrateInfluential work since 2022
- Pick up a classic book: Peptide microarraysThe most-reprinted book on the subject
- Read the landmark paper: Peptide and Small Molecule Microarray for High Throughput Cell Adhesion and Functional AssaysCited 300 times
- Go sideways: Epitope mappingA closely related topic
- Go sideways: Protein microarrayA closely related topic
📖 Definitions
No dictionary entry for this exact phrase.
🏆 Landmark papers (most cited)
Peptide and Small Molecule Microarray for High Throughput Cell Adhesion and Functional Assays
Epitope Mapping of Atlantic Salmon Major Allergen by Peptide Microarray Immunoassay
Target Specificity Analysis of the Abl Kinase using Peptide Microarray Data
Current advances in peptide and small molecule microarray technologies
Serodiagnosis of Echinococcus spp. Infection: Explorative Selection of Diagnostic Antigens by Peptide Microarray
Identification of amyloid β-peptide responsive genes by cDNA microarray technology: Involvement of RTP801 in amyloid β-peptide toxicity
Validation of peptide epitope microarray experiments and extraction of quality data
Peptide Microarray for High‐Throughput Determination of Phosphatase Specificity and Biology
🆕 Influential since 2022
Development of a peptide microarray-based metal-enhanced fluorescence assay for ultrasensitive detection of multiple matrix metalloproteinase activities by using a gold nanorod-polymer substrate
Microarray Chip-Based High-Throughput Screening of Neurofilament Light Chain Self-Assembling Peptide for Noninvasive Monitoring of Alzheimer’s Disease
Microarray-Based CD38 Peptide Probe Screening for Multiple Myeloma Imaging
Humoral Immune Response Profile of COVID-19 Reveals Severity and Variant-Specific Epitopes: Lessons from SARS-CoV-2 Peptide Microarray
Discovery of Phenolic Matrix Metalloproteinase Inhibitors by Peptide Microarray for Osteosarcoma Treatment
📚 Books worth reading
Peptide microarraysMarina Cretich, Marcella Chiari · 2009
Ranked by number of editions on Open Library, a rough measure of how lasting a book is.
🔗 Related topics
- Epitope mapping In immunology, epitope mapping is the process of experimentally identifying the binding site, or epitope, of an antibody on its target antigen (usually…
- Protein microarray A protein microarray (or protein chip) is a high-throughput method used to track the interactions and activities of proteins, and to determine their function…
- Epitope An epitope, (/ˈɛpɪtoʊp/) also known as antigenic determinant, is the part of an antigen that is recognized by the immune system, specifically by antibodies…
- Peptide biosensor A peptide biosensor is a type of biosensor that uses peptides or short amino acid fragments as the biorecognition element in detecting a specific analyte…
- Antibody microarray An antibody microarray (also known as antibody array) is a specific form of protein microarray. In this technology, a collection of captured antibodies…
- Peptide vaccine Peptide-based synthetic vaccines (epitope vaccines) are subunit vaccines made from peptides. The peptides mimic the epitopes of the antigen that triggers…
- Bio-layer interferometry Bio-layer interferometry (BLI) is an optical biosensing technology that analyzes biomolecular interactions in real-time without the need for fluorescent…
- Microarray Microarray at Wikipedia's sister projects Definitions from Wiktionary Textbooks from Wikibooks Resources from Wikiversity A microarray is a multiplex lab-on-a-c…