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Everything about PTPRO
Protein-coding gene in the species Homo sapiens
Receptor-type tyrosine-protein phosphatase O is an enzyme that in humans is encoded by the PTPRO gene. Wikipedia →
🧭 Start here: a 6-step reading path
- Read the overview: PTPROA 5-minute orientation
- Skim a recent paper: Age-related decline in hippocampal tyrosine phosphatase PTPRO is a mechanistic factor in chemotherapy-related cognitive impairmentInfluential work since 2022
- Read the landmark paper: Altered podocyte structure in GLEPP1 (Ptpro)-deficient mice associated with hypertension and low glomerular filtration rateCited 130 times
- Go sideways: PTPRJA closely related topic
- Go sideways: PTPN9A closely related topic
📖 Definitions
No dictionary entry for this exact phrase.
🗂️ The subject at a glance
No outline available.
🏆 Landmark papers (most cited)
Altered podocyte structure in GLEPP1 (Ptpro)-deficient mice associated with hypertension and low glomerular filtration rate
Disruption of PTPRO Causes Childhood-Onset Nephrotic Syndrome
PTPRO represses colorectal cancer tumorigenesis and progression by reprogramming fatty acid metabolism
Suppression of the protein tyrosine phosphatase receptor type O gene (PTPRO) by methylation in hepatocellular carcinomas
RETRACTED: Protein tyrosine phosphatase receptor-type O (PTPRO) exhibits characteristics of a candidate tumor suppressor in human lung cancer
Estrogen-Sensitive PTPRO Expression Represses Hepatocellular Carcinoma Progression by Control of STAT3
MiRNA‐548c‐5p downregulates inflammatory response in preeclampsia via targeting PTPRO
Expression of PTPRO during mouse development suggests involvement in axonogenesis and differentiation of NT‐3 and NGF‐dependent neurons
🆕 Influential since 2022
Age-related decline in hippocampal tyrosine phosphatase PTPRO is a mechanistic factor in chemotherapy-related cognitive impairment
PTPRO-related CD8+ T-cell signatures predict prognosis and immunotherapy response in patients with breast cancer
PTPRO inhibition ameliorates spinal cord injury through shifting microglial M1/M2 polarization via the NF-κB/STAT6 signaling pathway
Deletion or inhibition of PTPRO prevents ectopic fat accumulation and induces healthy obesity with markedly reduced systemic inflammation
PTPRO suppresses lymph node metastasis of esophageal carcinoma by dephosphorylating MET
📚 Books worth reading
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🔗 Related topics
- PTPRJ Receptor-type tyrosine-protein phosphatase eta is an enzyme that in humans is encoded by the PTPRJ gene. The protein encoded by this gene is a member of…
- PTPN9 Tyrosine-protein phosphatase non-receptor type 9 is an enzyme that in humans is encoded by the PTPN9 gene. The protein encoded by this gene is a member…
- PTPRB Receptor-type tyrosine-protein phosphatase beta or VE-PTP is an enzyme specifically expressed in endothelial cells that in humans is encoded by the PTPRB…
- PTPRE Receptor-type tyrosine-protein phosphatase epsilon is an enzyme that in humans is encoded by the PTPRE gene. The protein encoded by this gene is a member…
- PTPN7 Protein tyrosine phosphatase non-receptor type 7 is an enzyme that in humans is encoded by the PTPN7 gene. The protein encoded by this gene is a member…
- PTPRU Receptor-type tyrosine-protein phosphatase PCP-2 (also known as PTP-pi, PTP lambda, hPTP-J, PTPRO and PTP psi), is an enzyme that in humans is encoded…
- PTPN2 Tyrosine-protein phosphatase non-receptor type 2 is an enzyme that in humans is encoded by the PTPN2 gene. The protein encoded by this gene is a member…
- PTPRF Receptor-type tyrosine-protein phosphatase F is an enzyme that, in humans, is encoded by the PTPRF gene. The protein encoded by this gene is a member of…