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Everything about PTPRJ
Protein-coding gene in the species Homo sapiens
Receptor-type tyrosine-protein phosphatase eta is an enzyme that in humans is encoded by the PTPRJ gene. Wikipedia →
🧭 Start here: a 6-step reading path
- Read the overview: PTPRJA 5-minute orientation
- Skim a recent paper: miR-4443 promotes radiation resistance of esophageal squamous cell carcinoma via targeting PTPRJInfluential work since 2022
- Pick up a classic book: Expression of the receptor-like tyrosine phosphatase Byp (Ptprj) in the mouse inner ear and the development of methods for manipulating its expression in vivoThe most-reprinted book on the subject
- Read the landmark paper: Ptprj is a candidate for the mouse colon-cancer susceptibility locus Scc1 and is frequently deleted in human cancersCited 210 times
- Go sideways: PTPRSA closely related topic
- Go sideways: PTPRFA closely related topic
📖 Definitions
No dictionary entry for this exact phrase.
🗂️ The subject at a glance
🏆 Landmark papers (most cited)
Ptprj is a candidate for the mouse colon-cancer susceptibility locus Scc1 and is frequently deleted in human cancers
LOH of PTPRJ occurs early in colorectal cancer and is associated with chromosomal loss of 18q12–21
Cell transformation by FLT3 ITD in acute myeloid leukemia involves oxidative inactivation of the tumor suppressor protein-tyrosine phosphatase DEP-1/ PTPRJ
Somatic inactivating PTPRJ mutations and dysregulated pathways identified in canine malignant melanoma by integrated comparative genomic analysis
The tyrosine phosphatase PTPRJ/DEP-1 genotype affects thyroid carcinogenesis
Allelic association of the human homologue of the mouse modifier Ptprj with breast cancer
Loss-of-function mutations in PTPRJ cause a new form of inherited thrombocytopenia
Loss of the Protein‐Tyrosine Phosphatase DEP‐1/PTPRJ Drives Meningioma Cell Motility
🆕 Influential since 2022
miR-4443 promotes radiation resistance of esophageal squamous cell carcinoma via targeting PTPRJ
A heterophil/lymphocyte-selected population reveals the phosphatase PTPRJ is associated with immune defense in chickens
Phagocytosis mediated by the human granulocyte receptor CEACAM3 is limited by the receptor-type protein tyrosine phosphatase PTPRJ
Disrupting PTPRJ transmembrane-mediated oligomerization counteracts oncogenic receptor tyrosine kinase FLT3 ITD
High-fat diet alters N-glycosylation of PTPRJ in murine liver
📚 Books worth reading
Ranked by number of editions on Open Library, a rough measure of how lasting a book is.
🔗 Related topics
- PTPRS Receptor-type tyrosine-protein phosphatase S, also known as R-PTP-S, R-PTP-sigma, or PTPσ, is an enzyme that in humans is encoded by the PTPRS gene. The…
- PTPRF Receptor-type tyrosine-protein phosphatase F is an enzyme that, in humans, is encoded by the PTPRF gene. The protein encoded by this gene is a member of…
- PTPRE Receptor-type tyrosine-protein phosphatase epsilon is an enzyme that in humans is encoded by the PTPRE gene. The protein encoded by this gene is a member…
- PTPN7 Protein tyrosine phosphatase non-receptor type 7 is an enzyme that in humans is encoded by the PTPN7 gene. The protein encoded by this gene is a member…
- PTPRO Receptor-type tyrosine-protein phosphatase O is an enzyme that in humans is encoded by the PTPRO gene. This gene encodes a receptor-type protein tyrosine…
- PTPRH Receptor-type tyrosine-protein phosphatase H is an enzyme that in humans is encoded by the PTPRH gene. The protein encoded by this gene is a member of…
- PTPRM Receptor-type tyrosine-protein phosphatase mu is an enzyme that in humans is encoded by the PTPRM gene. The protein encoded by this gene is a member of…
- PTPRN2 Receptor-type tyrosine-protein phosphatase N2 (R-PTP-N2) also known as islet cell autoantigen-related protein (ICAAR) and phogrin is an enzyme that in…