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Everything about PRPF31
Protein-coding gene in the species Homo sapiens
PRP31 pre-mRNA processing factor 31 homolog , also known as PRPF31, is a protein which in humans is encoded by the PRPF31 gene. Wikipedia →
🧭 Start here: a 6-step reading path
- Read the overview: PRPF31A 5-minute orientation
- Skim a recent paper: Gene augmentation prevents retinal degeneration in a CRISPR/Cas9-based mouse model of PRPF31 retinitis pigmentosaInfluential work since 2022
- Read the landmark paper: Disrupted alternative splicing for genes implicated in splicing and ciliogenesis causes PRPF31 retinitis pigmentosaCited 233 times
- Go sideways: PRPF3A closely related topic
- Go sideways: Prp8A closely related topic
📖 Definitions
No dictionary entry for this exact phrase.
🗂️ The subject at a glance
🏆 Landmark papers (most cited)
Disrupted alternative splicing for genes implicated in splicing and ciliogenesis causes PRPF31 retinitis pigmentosa
Protein 61K, encoded by a gene (PRPF31) linked to autosomal dominant retinitis pigmentosa, is required for U4/U6·U5 tri‐snRNP formation and pre‐mRNA splicing
CNOT3 Is a Modifier of PRPF31 Mutations in Retinitis Pigmentosa with Incomplete Penetrance
Expression of PRPF31 mRNA in Patients with Autosomal Dominant Retinitis Pigmentosa: A Molecular Clue for Incomplete Penetrance?
Variation in retinitis pigmentosa-11 (PRPF31orRP11) gene expression between symptomatic and asymptomatic patients with dominantRP11mutations
Premature termination codons in PRPF31 cause retinitis pigmentosa via haploinsufficiency due to nonsense-mediated mRNA decay
Modeling PRPF31 retinitis pigmentosa using retinal pigment epithelium and organoids combined with gene augmentation rescue
Mutations in the Pre-mRNA Splicing-Factor Genes PRPF3 , PRPF8 , and PRPF31 in Spanish Families with Autosomal Dominant Retinitis Pigmentosa
🆕 Influential since 2022
Gene augmentation prevents retinal degeneration in a CRISPR/Cas9-based mouse model of PRPF31 retinitis pigmentosa
Activation of autophagy reverses progressive and deleterious protein aggregation in PRPF31 patient‐induced pluripotent stem cell‐derived retinal pigment epithelium cells
PRPF31-retinitis pigmentosa: Challenges and opportunities for clinical translation
A Precision Therapy Approach for Retinitis Pigmentosa 11 Using Splice-Switching Antisense Oligonucleotides to Restore the Open Reading Frame of PRPF31
Clinical and Genetic Findings in a Cohort of Patients with PRPF31-Associated Retinal Dystrophy
📚 Books worth reading
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🔗 Related topics
- PRPF3 U4/U6 small nuclear ribonucleoprotein Prp3 is a protein that in humans is encoded by the PRPF3 gene. The removal of introns from nuclear pre-mRNAs occurs…
- Prp8 Prp8 refers to both the Prp8 protein and Prp8 gene. Prp8's name originates from its involvement in pre-mRNA processing. The Prp8 protein is a large, highly…
- RP9 Retinitis pigmentosa 9 (autosomal dominant), also known as RP9 or PAP-1, is a protein which in humans is encoded by the RP9 gene. The removal of introns…
- Prp24 Prp24 (precursor RNA processing, gene 24) is a protein part of the pre-messenger RNA splicing process and aids the binding of U6 snRNA to U4 snRNA during…
- PRPF8 Pre-mRNA-processing-splicing factor 8 is a protein that in humans is encoded by the PRPF8 gene. Pre-mRNA splicing occurs in 2 sequential transesterification…
- PRPF4 U4/U6 small nuclear ribonucleoprotein Prp4 is a protein that is found in humans and encoded by the PRPF4 gene. The removal of introns from nuclear pre-mRNAs…
- RP1 Oxygen-regulated protein 1 also known as retinitis pigmentosa 1 protein (RP1) is a protein that in humans is encoded by the RP1 gene. This gene encodes…
- Spliceosome A spliceosome is a large complex of proteins and RNA (ribonucleoprotein) that functions to remove introns from pre-mRNA, a process called RNA splicing…