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Everything about PRPF3
Protein-coding gene in humans
U4/U6 small nuclear ribonucleoprotein Prp3 is a protein that in humans is encoded by the PRPF3 gene. Wikipedia →
🧭 Start here: a 6-step reading path
- Read the overview: PRPF3A 5-minute orientation
- Skim a recent paper: Integrative analysis based on ATAC-seq and RNA-seq reveals a novel oncogene PRPF3 in hepatocellular carcinomaInfluential work since 2022
- Read the landmark paper: Mutations in the Pre-mRNA Splicing-Factor Genes PRPF3 , PRPF8 , and PRPF31 in Spanish Families with Autosomal Dominant Retinitis PigmentosaCited 78 times
- Go sideways: PRPF31A closely related topic
- Go sideways: PRPF8A closely related topic
📖 Definitions
No dictionary entry for this exact phrase.
🗂️ The subject at a glance
🏆 Landmark papers (most cited)
Mutations in the Pre-mRNA Splicing-Factor Genes PRPF3 , PRPF8 , and PRPF31 in Spanish Families with Autosomal Dominant Retinitis Pigmentosa
Temporal and Tissue Specific Regulation of RP-Associated Splicing Factor Genes PRPF3, PRPF31 and PRPC8—Implications in the Pathogenesis of RP
Mutations in splicing factor PRPF3, causing retinal degeneration, form detrimental aggregates in photoreceptor cells
Prognostic potential of PRPF3 in hepatocellular carcinoma
Decreased Levels of the RNA Splicing Factor Prpf3 in Mice and Zebrafish Do Not Cause Photoreceptor Degeneration
EPS15R, TASP1, and PRPF3 Are Novel Disease Candidate Genes Targeted by HNF4α Splice Variants in Hepatocellular Carcinomas
Two novel mutations in PRPF3 causing autosomal dominant retinitis pigmentosa
TMEM43 promotes pancreatic cancer progression by stabilizing PRPF3 and regulating RAP2B/ERK axis
🆕 Influential since 2022
Integrative analysis based on ATAC-seq and RNA-seq reveals a novel oncogene PRPF3 in hepatocellular carcinoma
Correction: TMEM43 promotes pancreatic cancer progression by stabilizing PRPF3 and regulating RAP2B/ERK axis
Functional and Network Analysis of PRPF3: Insights into Spliceosomal Regulation and Disease Associations
FACS-based dual fluorescence reporter assay demonstrates efficacy of antisense oligonucleotide therapy of novel PRPF3 intronic splice variant
📚 Books worth reading
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🔗 Related topics
- PRPF31 PRP31 pre-mRNA processing factor 31 homolog (S. cerevisiae), also known as PRPF31, is a protein which in humans is encoded by the PRPF31 gene. PRPF31 is…
- PRPF8 Pre-mRNA-processing-splicing factor 8 is a protein that in humans is encoded by the PRPF8 gene. Pre-mRNA splicing occurs in 2 sequential transesterification…
- PRPF4 U4/U6 small nuclear ribonucleoprotein Prp4 is a protein that is found in humans and encoded by the PRPF4 gene. The removal of introns from nuclear pre-mRNAs…
- PPIH Peptidyl-prolyl cis-trans isomerase H is an enzyme that in humans is encoded by the PPIH gene. The protein encoded by this gene is a member of the peptidyl-prol…
- U4 spliceosomal RNA The U4 small nuclear Ribo-Nucleic Acid (U4 snRNA) is a non-coding RNA component of the major or U2-dependent spliceosome – a eukaryotic molecular machine…
- RP9 Retinitis pigmentosa 9 (autosomal dominant), also known as RP9 or PAP-1, is a protein which in humans is encoded by the RP9 gene. The removal of introns…
- Prp8 Prp8 refers to both the Prp8 protein and Prp8 gene. Prp8's name originates from its involvement in pre-mRNA processing. The Prp8 protein is a large, highly…
- Spliceosome A spliceosome is a large complex of proteins and RNA (ribonucleoprotein) that functions to remove introns from pre-mRNA, a process called RNA splicing…