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Everything about Microprocessor complex
Protein involved in processing RNA in animal cells
The microprocessor complex is a protein complex involved in the early stages of processing microRNA (miRNA) and RNA interference (RNAi) in animal cells. The complex is minimally composed of the ribonuclease enzyme Drosha and the dimeric RNA-binding protein DGCR8, and cleaves primary miRNA substrates to pre-miRNA in the cell nucleus. Microprocessor is also the smaller of the two multi-protein complexes that contain human Drosha. Wikipedia →
🧭 Start here: a 6-step reading path
- Read the overview: Microprocessor complexA 5-minute orientation
- Skim a recent paper: Generating dual-active species by triple-atom sites through peroxymonosulfate activation for treating micropollutants in complex waterInfluential work since 2022
- Pick up a classic book: Testing complex and embedded systemsThe most-reprinted book on the subject
- Read the landmark paper: Processing of primary microRNAs by the Microprocessor complexCited 2,408 times
- Go sideways: DroshaA closely related topic
- Go sideways: Microprocessor complex subunit DGCR8A closely related topic
📖 Definitions
No dictionary entry for this exact phrase.
🗂️ The subject at a glance
🏆 Landmark papers (most cited)
Processing of primary microRNAs by the Microprocessor complex
The Microprocessor complex mediates the genesis of microRNAs
BRCA1 regulates microRNA biogenesis via the DROSHA microprocessor complex
Functional Association of the Microprocessor Complex with the Spliceosome
Mutant p53 inhibits miRNA biogenesis by interfering with the microprocessor complex
Control of ribosomal protein synthesis by the Microprocessor complex
A functional connection between the Microprocessor and a variant NEXT complex
WBP2 inhibits microRNA biogenesis via interaction with the microprocessor complex
🆕 Influential since 2022
Generating dual-active species by triple-atom sites through peroxymonosulfate activation for treating micropollutants in complex water
The Ubiquitin-specific Protease USP36 Associates with the Microprocessor Complex and Regulates miRNA Biogenesis by SUMOylating DGCR8
Assessing Microprocessor complex mutations with a Microsensor system
Nucleolin’s Role in the Biogenesis of Pri‐miRNA 16 by the Microprocessor Complex: An In silico Approach
📚 Books worth reading
Testing complex and embedded systemsKim H. Pries · 2010
Ranked by number of editions on Open Library, a rough measure of how lasting a book is.
🔗 Related topics
- Drosha Drosha is a Class 2 ribonuclease III enzyme that in humans is encoded by the DROSHA (formerly RNASEN) gene. It is the primary nuclease that executes the…
- Microprocessor complex subunit DGCR8 The microprocessor complex subunit DGCR8 (DiGeorge syndrome critical region 8) is a protein that in humans is encoded by the DGCR8 gene. In other animals…
- DCL1 DCL1 (an abbreviation of Dicer-like 1) is a gene in plants that codes for the DCL1 protein, a ribonuclease III enzyme involved in processing double-stranded…
- Dicer Dicer, also known as endoribonuclease Dicer or helicase with RNase motif, is an enzyme that in humans is encoded by the DICER1 gene. Being part of the…
- MicroRNA Micro ribonucleic acid (microRNA, miRNA, μRNA) are small, single-stranded, non-coding RNA molecules containing 21–23 nucleotides. Found in plants, animals…
- V. Narry Kim V. Narry Kim (Korean: 김빛내리; born 18 June 1969) is a South Korean biochemist and microbiologist, best known for her work on microRNA biogenesis. Her pioneering…
- Ribonuclease III Ribonuclease III (RNase III or RNase C) (BRENDA 3.1.26.3) is a type of ribonuclease that recognizes dsRNA and cleaves it at specific targeted locations…
- RNA-induced silencing complex The RNA-induced silencing complex, or RISC, is a multiprotein complex, specifically a ribonucleoprotein, which functions in gene silencing via a variety…