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Everything about DCL1
Protein coding gene in plants
DCL1 is a gene in plants that codes for the DCL1 protein, a ribonuclease III enzyme involved in processing double-stranded RNA (dsRNA) and microRNA (miRNA). Although DCL1, also called Endoribonuclease Dicer homolog 1, is named for its homology with the metazoan protein Dicer, its role in miRNA biogenesis is somewhat different, due to substantial differences in miRNA maturation processes between plants and animals, as well due to additional downstream plant-specific pathways, where DCL1 paralogs like DCL4 participate, such trans-acting siRNA biogenesis. Wikipedia →
🧭 Start here: a 6-step reading path
- Read the overview: DCL1A 5-minute orientation
- Skim a recent paper: Structural determinants in the miRNA/miRNA* duplex and the DCL1 PAZ domain for precise and efficient plant miRNA processingInfluential work since 2022
- Pick up a classic book: The Merchant of VeniceThe most-reprinted book on the subject
- Read the landmark paper: The interaction between DCL1 and HYL1 is important for efficient and precise processing of pri-miRNA in plant microRNA biogenesisCited 434 times
- Go sideways: DCL5A closely related topic
- Go sideways: DroshaA closely related topic
📖 Definitions
No dictionary entry for this exact phrase.
🗂️ The subject at a glance
🏆 Landmark papers (most cited)
The interaction between DCL1 and HYL1 is important for efficient and precise processing of pri-miRNA in plant microRNA biogenesis
The RNA-binding proteins HYL1 and SE promote accurate in vitro processing of pri-miRNA by DCL1
Arabidopsis DRB4, AGO1, AGO7, and RDR6 participate in a DCL4-initiated antiviral RNA silencing pathway negatively regulated by DCL1
Arabidopsis primary microRNA processing proteins HYL1 and DCL1 define a nuclear body distinct from the Cajal body
Diversification of the Core RNA Interference Machinery in Chlamydomonas reinhardtii and the Role of DCL1 in Transposon Silencing
SINE RNA Induces Severe Developmental Defects in Arabidopsis thaliana and Interacts with HYL1 (DRB1), a Key Member of the DCL1 Complex
A dominant mutation in DCL1 suppresses the hyl1 mutant phenotype by promoting the processing of miRNA
Light-stabilized FHA2 suppresses miRNA biogenesis through interactions with DCL1 and HYL1
🆕 Influential since 2022
Structural determinants in the miRNA/miRNA* duplex and the DCL1 PAZ domain for precise and efficient plant miRNA processing
Safeguard DCL2-Dependent 22-nt siRNA generation by DCL1
Form follows function – structural interplay between DCL1 and pri-miRNAs
Key RNA elements influencing DCL1 cleavage in plant microRNA biogenesis
A HIGS approach targeting the DCL1, CYP51 and CHS genes of the pathogen to control Colletotrichum acutatum infection of strawberry
📚 Books worth reading
The Merchant of VeniceWilliam Shakespeare · 1600
Life and letters of Brooke Foss Westcott, D.D., D.C.LArthur Westcott · 1903
Journal of the American Oriental SocietyAmerican Oriental Society · 1843
The MonthSimpkin, Marshall, and Co. · 1864
Corporat leverage - revisitedSandip Sinha · 2009
Journal of a special meeting of the Synod of the Diocese of Toronto held for the election of a bishopChurch of England. Diocese of Toronto. · 1879
Clinical Image-Based Procedures, Distributed and Collaborative Learning, Artificial Intelligence for Combating COVID-19 and Secure and Privacy-Preserving Machine LearningCristina Oyarzun Laura, M. Jorge Cardoso · 2021- 📕Catalogue of valuable printed books and illuminated and other manuscripts comprising the property of the late Sir Philip Duncombe, Bt. ...; the property of the late Paul Butler, Esq. of Wyck Hill, Glos. ...; the property of the late F. Du Cane Godman, Esq., D.C.L., F.R.S., Trustee of the British Museum and joint author of the Biologica Centrali Americana ... also a few important medieval manuscripts ...Sotheby, Wilkinson & Hodge · 1921
Ranked by number of editions on Open Library, a rough measure of how lasting a book is.
🔗 Related topics
- DCL5 DICER-LIKE 5 (DCL5) is a plant Dicer-like endoribonuclease that functions in the biogenesis of 24-nucleotide reproductive phased small interfering RNAs…
- Drosha Drosha is a Class 2 ribonuclease III enzyme that in humans is encoded by the DROSHA (formerly RNASEN) gene. It is the primary nuclease that executes the…
- DCL3 DCL3 (Dicer-like 3) is a plant gene that encodes a ribonuclease III enzyme involved in the RNA-directed DNA methylation (RdDM) pathway, a plant-specific…
- DCL4 DCL4 (Dicer-like 4) is a plant gene that encodes an enzyme involved in RNA silencing, a process by which cells regulate gene expression and defend against…
- Dicer Dicer, also known as endoribonuclease Dicer or helicase with RNase motif, is an enzyme that in humans is encoded by the DICER1 gene. Being part of the…
- DCL2 DCL2 (an abbreviation of Dicer-like 2) is a gene in plants that codes for the DCL2 protein, a ribonuclease III enzyme involved in processing exogenous…
- Trans-acting siRNA Trans-acting siRNA (abbreviated "ta-siRNA" or "tasiRNA") are a class of small interfering RNA (siRNA) that repress gene expression through post-transcriptional…
- Microprocessor complex subunit DGCR8 The microprocessor complex subunit DGCR8 (DiGeorge syndrome critical region 8) is a protein that in humans is encoded by the DGCR8 gene. In other animals…