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Everything about DCL3

Plant gene

DCL3 is a plant gene that encodes a ribonuclease III enzyme involved in the RNA-directed DNA methylation (RdDM) pathway, a plant-specific mechanism of transcriptional gene silencing. DCL3 processes double-stranded RNA (dsRNA) precursors into 24-nucleotide small interfering RNAs (siRNAs) that guide epigenetic modification of target genomic loci. Wikipedia →

🧭 Start here: a 6-step reading path

  1. Read the overview: DCL3A 5-minute orientation
  2. Skim a recent paper: The RNA-binding domain of DCL3 is required for long-distance RNAi signalingInfluential work since 2022
  3. Pick up a classic book: Journal of the American Oriental SocietyThe most-reprinted book on the subject
  4. Read the landmark paper: Reaction Mechanisms of Pol IV, RDR2, and DCL3 Drive RNA Channeling in the siRNA-Directed DNA Methylation PathwayCited 129 times
  5. Go sideways: RNA-directed DNA methylationA closely related topic
  6. Go sideways: RNA polymerase VA closely related topic

📖 Definitions

No dictionary entry for this exact phrase.

🗂️ The subject at a glance

  1. Function
  2. Evolutionary history

🏆 Landmark papers (most cited)

🆕 Influential since 2022

📚 Books worth reading

Ranked by number of editions on Open Library, a rough measure of how lasting a book is.

🔗 Related topics