Live briefing
Everything about Long non-coding RNA
Non-protein coding transcripts longer than 200 nucleotides
Long non-coding RNAs are a type of RNA, generally defined as transcripts of more than 200 nucleotides that are not translated into protein. This arbitrary limit distinguishes long ncRNAs from small non-coding RNAs, such as microRNAs (miRNAs), small interfering RNAs (siRNAs), Piwi-interacting RNAs (piRNAs), small nucleolar RNAs (snoRNAs), and other short RNAs. Given that some genuine lncRNAs may encode small proteins, the latest definition of lncRNA is a class of transcripts of over 200 nucleotides that have no or limited coding capacity. Wikipedia →
🧭 Start here: a 6-step reading path
- Read the overview: Long non-coding RNAA 5-minute orientation
- Skim a recent paper: Long non-coding RNAs: definitions, functions, challenges and recommendationsInfluential work since 2022
- Pick up a classic book: Junk DNAThe most-reprinted book on the subject
- Read the landmark paper: Human Cancer Long Non-Coding RNA TranscriptomesCited 298 times
- Go sideways: XISTA closely related topic
- Go sideways: HOTAIRA closely related topic
📖 Definitions
No dictionary entry for this exact phrase.
🗂️ The subject at a glance
🏆 Landmark papers (most cited)
Human Cancer Long Non-Coding RNA Transcriptomes
Long Non-Coding RNA in Cancer
Long non-coding RNA and chromatin remodeling
MALAT1 Long Non-Coding RNA: Functional Implications
Long non‐coding RNA modifies chromatin
MALAT1 long non-coding RNA in cancer
PLncDB: plant long non-coding RNA database
HOTAIR: a cancer-related long non-coding RNA
🆕 Influential since 2022
Long non-coding RNAs: definitions, functions, challenges and recommendations
Long non-coding RNA mediated drug resistance in breast cancer
Long non-coding RNA-encoded micropeptides: functions, mechanisms and implications
The Long Non-Coding RNA ANRIL in Cancers
Emerging roles of long non-coding RNA in depression
📚 Books worth reading
Junk DNANessa Carey · 2015
Molecular Biology of Long Non-coding RNAsAhmad M. Khalil, Jeff Coller · 2013
Ranked by number of editions on Open Library, a rough measure of how lasting a book is.
🔗 Related topics
- XIST Xist (X-inactive specific transcript) is a non-coding RNA transcribed from the X chromosome of the placental mammals that acts as a major effector of the…
- HOTAIR HOTAIR (for HOX transcript antisense RNA) is a human gene located between HOXC11 and HOXC12 on chromosome 12. It is the first example of an RNA expressed…
- HOXA11-AS1 HOXA11-AS lncRNA is a long non-coding RNA from the antisense strand in the homeobox A (HOXA gene). The HOX gene contains four clusters (A, B, C, and D)…
- Epigenetics of human development Epigenetics play an important role in animal development, including the development of human beings. Various epigenetic markers serve different roles that…
- Non-coding RNA A non-coding RNA (ncRNA) is a functional RNA molecule that is not translated into a protein. The DNA sequence from which a functional non-coding RNA is…
- Enhancer RNA Enhancer RNAs (eRNAs) represent a class of relatively long non-coding RNA molecules (50–2000 nucleotides) transcribed from the DNA sequence of enhancer…
- HOTTIP In molecular biology, HOTTIP (HOXA transcript at the distal tip) is a long non-coding RNA. The gene encoding HOTTIP is located at the 5′ tip of the HOXA…
- Antisense RNA Antisense RNA (asRNA), also referred to as antisense transcript, natural antisense transcript (NAT) or antisense oligonucleotide, is a single stranded…