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Everything about Bioinformatics

Computational analysis of large, complex sets of biological data

Bioinformatics is an interdisciplinary field of science that develops computational methods and software tools for understanding biological data, especially when the data sets are large and complex. Bioinformatics integrates principles from biology, chemistry, physics, computer science, data science, computer programming, information engineering, mathematics, and statistics to analyze and interpret biological data. This process can sometimes be referred to as computational biology; however, the distinction between the two terms is often disputed. The term computational biology can refer to building and using models of biological systems. Wikipedia →

🧭 Start here: a 6-step reading path

  1. Read the overview: BioinformaticsA 5-minute orientation
  2. Skim a recent paper: Introducing the Bacterial and Viral Bioinformatics Resource Center (BV-BRC): a resource combining PATRIC, IRD and ViPRInfluential work since 2022
  3. Pick up a classic book: Advances in visual computingThe most-reprinted book on the subject
  4. Read the landmark paper: Systematic and integrative analysis of large gene lists using DAVID bioinformatics resourcesCited 32,433 times
  5. Go sideways: Sequence analysisA closely related topic
  6. Go sideways: GenomicsA closely related topic

📖 Definitions

Noun A field of science in which biology, computer science, and information technology merge into a single discipline to analyse biological information using computers and statistical techniques.

🗂️ The subject at a glance

  1. History
  2. Goals
  3. Sequence analysis
  4. Gene and protein expression
  5. Analysis of cellular organization
  6. Structural bioinformatics
  7. Network and systems biology
  8. Biodiversity informatics
  9. Others
  10. Databases
  11. Software and tools
  12. Education platforms

🏆 Landmark papers (most cited)

🆕 Influential since 2022

📚 Books worth reading

Ranked by number of editions on Open Library, a rough measure of how lasting a book is.

🔗 Related topics