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Everything about Sequence analysis

Identification and study of genomic sequences

In bioinformatics, sequence analysis is the process of subjecting a DNA, RNA or peptide sequence to any of a wide range of analytical methods to understand its features, function, structure, or evolution. It can be performed on the entire genome, transcriptome or proteome of an organism, and can also involve only selected segments or regions, like tandem repeats and transposable elements. Methodologies used include sequence alignment, searches against biological databases, and others. Wikipedia →

🧭 Start here: a 6-step reading path

  1. Read the overview: Sequence analysisA 5-minute orientation
  2. Skim a recent paper: Search and sequence analysis tools services from EMBL-EBI in 2022Influential work since 2022
  3. Pick up a classic book: Gene Cloning and DNA AnalysisThe most-reprinted book on the subject
  4. Read the landmark paper: The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis toolsCited 31,926 times
  5. Go sideways: BioinformaticsA closely related topic
  6. Go sideways: Gene predictionA closely related topic

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🏆 Landmark papers (most cited)

🆕 Influential since 2022

📚 Books worth reading

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