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Everything about Volcano plot (statistics)

Type of scatter plot

In statistics, a volcano plot is a type of scatter-plot that is used to quickly identify changes in large data sets composed of replicate data. It plots significance versus fold-change on the y and x axes, respectively. These plots are increasingly common in omic experiments such as genomics, proteomics, and metabolomics where one often has a list of many thousands of replicate data points between two conditions and one wishes to quickly identify the most meaningful changes. A volcano plot combines a measure of statistical significance from a statistical test with the magnitude of the change, enabling quick visual identification of those data-points that display large magnitude changes that are also statistically significant. Wikipedia →

đź§­ Start here: a 6-step reading path

  1. Read the overview: Volcano plot (statistics)A 5-minute orientation
  2. Pick up a classic book: The Conspirators HierarchyThe most-reprinted book on the subject
  3. Read the landmark paper: Using volcano plots and regularized-chi statistics in genetic association studiesCited 29 times
  4. Go sideways: MA plotA closely related topic
  5. Go sideways: Dual-flashlight plotA closely related topic

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🏆 Landmark papers (most cited)

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