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Everything about SCN4B
Protein-coding gene in the species Homo sapiens
Sodium channel β-subunit 4, also known as SCN4B or Naβ4, is an auxiliary sodium channel subunit that can alter the kinetics of sodium channels. The protein is encoded by the SCN4B gene. Mutations in the SCN4B are associated with long QT syndrome. Wikipedia →
🧭 Start here: a 6-step reading path
- Read the overview: SCN4BA 5-minute orientation
- Skim a recent paper: SCN4B inhibits the progression of lung adenocarcinoma and is associated with better prognosisInfluential work since 2022
- Pick up a classic book: Strukturelle und kristallphysikalische Charakterisierung der komplexen Thiosulfate vom Typ A₉[B(S₂O₃)₄]X₂The most-reprinted book on the subject
- Read the landmark paper: SCN4B -Encoded Sodium Channel β4 Subunit in Congenital Long-QT SyndromeCited 320 times
- Go sideways: SCN2BA closely related topic
- Go sideways: SCN3BA closely related topic
📖 Definitions
No dictionary entry for this exact phrase.
🗂️ The subject at a glance
No outline available.
🏆 Landmark papers (most cited)
SCN4B -Encoded Sodium Channel β4 Subunit in Congenital Long-QT Syndrome
Mutations of the SCN4B-encoded sodium channel β4 subunit in familial atrial fibrillation
SCN4B acts as a metastasis-suppressor gene preventing hyperactivation of cell migration in breast cancer
miR-424-5p promotes the proliferation and metastasis of colorectal cancer by directly targeting SCN4B
Significant association of rare variant p.Gly8Ser in cardiac sodium channel β4‐subunit SCN4B with atrial fibrillation
Preserved SCN4B expression is an independent indicator of favorable recurrence-free survival in classical papillary thyroid cancer
Identification of rare variants in cardiac sodium channel β4-subunit gene SCN4B associated with ventricular tachycardia
Scn4b regulates the hypnotic effects of ethanol and other sedative drugs
🆕 Influential since 2022
SCN4B inhibits the progression of lung adenocarcinoma and is associated with better prognosis
Anti‐NSCLC role of SCN4B by negative regulation of the cGMP‐PKG pathway: Integrated utilization of bioinformatics analysis and in vitro assay validation
Low Expression of SCN4B Predicts Poor Prognosis in Non-small Cell Lung Cancer
Suppressive role of SCN4B in the epithelial‑mesenchymal transition of lung adenocarcinoma
Analysis of the molecular targets of anesthetics SCN4B and ARRB1 in lung adenocarcinoma based on electrochemical sensors: An integrated transcriptomic investigation
📚 Books worth reading
- 📕Strukturelle und kristallphysikalische Charakterisierung der komplexen Thiosulfate vom Typ A₉[B(S₂O₃)₄]X₂Peter Held · 1994
Ranked by number of editions on Open Library, a rough measure of how lasting a book is.
🔗 Related topics
- SCN2B Sodium channel subunit beta-2 is a protein that in humans is encoded by the SCN2B gene. Sodium channel GRCh38: Ensembl release 89: ENSG00000149575 – Ensembl…
- SCN3B Sodium channel subunit beta-3 is a protein that in humans is encoded by the SCN3B gene. Two alternatively spliced variants, encoding the same protein,…
- CACNB3 Voltage-dependent L-type calcium channel subunit beta-3 is a protein that in humans is encoded by the CACNB3 gene. Voltage-dependent calcium channel GRCh38:…
- SCNN1D The SCNN1D gene encodes for the δ (delta) subunit of the epithelial sodium channel ENaC in vertebrates. ENaC is assembled as a heterotrimer composed of…
- SCN1B Sodium channel subunit beta-1 is a protein that in humans is encoded by the SCN1B gene. Voltage-gated sodium channels are essential for the generation…
- SCN3A Sodium channel, voltage-gated, type III, alpha subunit (SCN3A) is a protein that in humans is encoded by the SCN3A gene. Voltage-gated sodium channels…
- CACNA2D1 Voltage-dependent calcium channel subunit alpha-2/delta-1 is a protein that in humans is encoded by the CACNA2D1 gene. The CACNA2D1 gene is located on…
- SCN4A Sodium channel protein type 4 subunit alpha is a protein that in humans is encoded by the SCN4A gene. The Nav1.4 voltage-gated sodium channel is encoded…