Everything about Prodine

🧭 Start here: a 6-step reading path

1. Read the overview: ProdineA 5-minute orientation
2. Pick up a classic book: Absolute stereochemistry an analgesic potency of Alpha and Beta prodine enantiomersThe most-reprinted book on the subject
3. Read the landmark paper: Alpha- and Beta-Prodine Type CompoundsCited 27 times
4. Go sideways: PiminodineA closely related topic
5. Go sideways: PethidineA closely related topic

🏆 Landmark papers (most cited)

• Alpha- and Beta-Prodine Type Compounds

  A. H. Beckett, A. F. Casy, G. Kirk · 1959 · Journal of Medicinal and Pharmaceutical Chemistry · 27 citations

• Combined analgesic/neuroleptic activity in N-butyrophenone prodine-like compounds

  M. A. Iorio, T. Paszkowska Reymer, V. Frigeni · 1987 · Journal of Medicinal Chemistry · 24 citations

• Quantum chemical studies of meperidine and prodine

  Gilda H. Loew, J. Randal Jester · 1975 · Journal of Medicinal Chemistry · 18 citations

• Alpha- and Beta-Prodine Type Compounds: Configurational Studies

  A H Beckett, A F Casy, G Kirk · 1957 · Journal of Pharmacy and Pharmacology · 18 citations

• A study of the biologically active conformers for prodine opiates and their derivatives

  Mark Froimowitz, Peter Kollman · 1984 · Journal of Computational Chemistry · 16 citations

• 2-Azabicyclo[2.2.2]octane analogues of the prodine analgetics

  C. Randall Clark, John M. Holbrook, Ronald F. Borne · 1976 · Journal of Medicinal Chemistry · 12 citations

• Stereochemical studies on medicinal agents. 11. Metabolism and distribution of prodine isomers in mice

  M. M. Abdel-Monem, D. L. Larson, H. J. Kupferberg · 1972 · Journal of Medicinal Chemistry · 12 citations

• Interaction of monoamine oxidase B with analogs of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine derived from prodine-type analgesics

  Arnold Brossi, Wieslaw P. Gessner, Richard R. Fritz · 1986 · Journal of Medicinal Chemistry · 11 citations

📚 Books worth reading

• 📕Absolute stereochemistry an analgesic potency of Alpha and Beta prodine enantiomersDennis LeRoy Larson · 1969

Ranked by number of editions on Open Library, a rough measure of how lasting a book is.

🔗 Related topics

• Piminodine Piminodine (Alvodine) is an opioid analgesic that is an analogue of pethidine (meperidine). It was used in medicine briefly during the 1960s and 70s, but…
• Pethidine Pethidine, also known as meperidine and sold under the brand name Demerol among others, is a fully synthetic opioid pain medication of the phenylpiperidine…
• Hydroxypethidine Hydroxypethidine (Bemidone) is an opioid analgesic that is an analogue of the more commonly used pethidine (meperidine). Hydroxypethidine is slightly more…
• Meprodine Meprodine is an opioid analgesic that is an analogue of pethidine (meperidine). It is closely related to the drug prodine, the only difference being that…
• Trimeperidine Trimeperidine, sold under the brand name Promedol, is an opioid analgesic that is an analogue of prodine. It was developed in the early 1950s in the Soviet…
• Levallorphan Levallorphan (INN, BAN; USAN levallorphan tartrate; brand names Lorfan, Naloxifan, and Naloxiphan) is an opioid modulator of the morphinan family used…
• Hydromorphone Hydromorphone, also known as dihydromorphinone, and sold under the brand name Dilaudid among others, is a morphinan opioid used to treat moderate to severe…
• Piritramide Piritramide (R-3365, trade names Dipidolor, Piridolan, Pirium and others) is a synthetic opioid analgesic (narcotic painkiller) that is marketed in certain…