Everything About ___
Live briefing

Everything about Piritramide

Synthetic opioid

Piritramide is a synthetic opioid analgesic that is marketed in certain European countries including: Austria, Belgium, Czech Republic, Slovenia, Germany and the Netherlands. It comes in free form, is about 0.75x times as potent as morphine and is given parenterally for the treatment of severe pain. Nausea, vomiting, respiratory depression and constipation are believed to be less frequent with piritramide than with morphine, and it produces more rapid-onset analgesia when compared to morphine and pethidine. After intravenous administration the onset of analgesia is as little as 1–2 minutes, which may be related to its great lipophilicity. The analgesic and sedative effects of piritramide are believed to be potentiated with phenothiazines and its emetic (nausea/vomiting-inducing) effects are suppressed. The volume of distribution is 0.7-1 L/kg after a single dose, 4.7-6 L/kg after steady-state concentrations are achieved and up to 11.1 L/kg after prolonged dosing. Wikipedia →

🧭 Start here: a 6-step reading path

  1. Read the overview: PiritramideA 5-minute orientation
  2. Skim a recent paper: Eigenständige Analgesie mit Piritramid durch Notfallsanitäter – retrospektive Auswertung der elektronischen EinsatzdokumentationInfluential work since 2022
  3. Pick up a classic book: Postoperative Schmerzbekampfung mit epiduralem Piritramid (Dipidolor[registered trademark])The most-reprinted book on the subject
  4. Read the landmark paper: Contractile Responses to Morphine, Piritramide, Meperidine, and Fentanyl: A Comparative Study of Effects on the Isolated Ventricular MyocardiumCited 104 times
  5. Go sideways: DihydromorphineA closely related topic
  6. Go sideways: NalbuphineA closely related topic

📖 Definitions

Noun A particular narcotic painkiller.

🗂️ The subject at a glance

No outline available.

🏆 Landmark papers (most cited)

🆕 Influential since 2022

📚 Books worth reading

Ranked by number of editions on Open Library, a rough measure of how lasting a book is.

🔗 Related topics