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Everything about PTPN3
Protein-coding gene in the species Homo sapiens
Tyrosine-protein phosphatase non-receptor type 3 is an enzyme that in humans is encoded by the PTPN3 gene. Wikipedia →
🧭 Start here: a 6-step reading path
- Read the overview: PTPN3A 5-minute orientation
- Skim a recent paper: Clinicopathological correlation of PTPN3 expression in breast cancer and in silico drug screening against PTPN3 for therapeuticsInfluential work since 2022
- Pick up a classic book: Klucz do solidarności wielkiej rodziny intelektualnejThe most-reprinted book on the subject
- Read the landmark paper: Activating Mutations in PTPN3 Promote Cholangiocarcinoma Cell Proliferation and Migration and Are Associated With Tumor Recurrence in PatientsCited 111 times
- Go sideways: PTPN7A closely related topic
- Go sideways: PTPN12A closely related topic
📖 Definitions
No dictionary entry for this exact phrase.
🗂️ The subject at a glance
🏆 Landmark papers (most cited)
Activating Mutations in PTPN3 Promote Cholangiocarcinoma Cell Proliferation and Migration and Are Associated With Tumor Recurrence in Patients
Degradation of Tyrosine Phosphatase PTPN3 (PTPH1) by Association with Oncogenic HumanPapillomavirus E6 Proteins
Discovery of ALK ‐ PTPN3 gene fusion from human non‐small cell lung carcinoma cell line using next generation RNA sequencing
Protein tyrosine phosphatase PTPN3 inhibits lung cancer cell proliferation and migration by promoting EGFR endocytic degradation
Reciprocal allosteric regulation of p38γ and PTPN3 involves a PDZ domain–modulated complex formation
PTPN3 suppresses lung cancer cell invasiveness by counteracting Src-mediated DAAM1 activation and actin polymerization
The FERM and PDZ Domain-Containing Protein Tyrosine Phosphatases, PTPN4 and PTPN3, Are Both Dispensable for T Cell Receptor Signal Transduction
PTPN3 acts as a tumor suppressor and boosts TGF‐β signaling independent of its phosphatase activity
🆕 Influential since 2022
Clinicopathological correlation of PTPN3 expression in breast cancer and in silico drug screening against PTPN3 for therapeutics
Identification and verification of PTPN3 as a novel biomarker in predicting cancer prognosis, immunity, and immunotherapeutic efficacy
Association of SNPs within PTPN3 gene with wool production and growth traits in a dual-purpose sheep population
Interactions of the protein tyrosine phosphatase PTPN3 with viral and cellular partners through its PDZ domain: insights into structural determinants and phosphatase activity
PTPN3 inhibition contributes to the activation of the dendritic cell function to be a promising new immunotherapy target
📚 Books worth reading
Klucz do solidarności wielkiej rodziny intelektualnejHeliodor Święcicki · 2009
Ranked by number of editions on Open Library, a rough measure of how lasting a book is.
🔗 Related topics
- PTPN7 Protein tyrosine phosphatase non-receptor type 7 is an enzyme that in humans is encoded by the PTPN7 gene. The protein encoded by this gene is a member…
- PTPN12 Tyrosine-protein phosphatase non-receptor type 12 is an enzyme that in humans is encoded by the PTPN12 gene. The protein encoded by this gene is a member…
- PTPN2 Tyrosine-protein phosphatase non-receptor type 2 is an enzyme that in humans is encoded by the PTPN2 gene. The protein encoded by this gene is a member…
- PTPN21 Tyrosine-protein phosphatase non-receptor type 21 is an enzyme that in humans is encoded by the PTPN21 gene. The protein encoded by this gene is a member…
- PTPRJ Receptor-type tyrosine-protein phosphatase eta is an enzyme that in humans is encoded by the PTPRJ gene. The protein encoded by this gene is a member of…
- PSTPIP1 Proline-serine-threonine phosphatase-interacting protein 1 is an enzyme that in humans is encoded by the PSTPIP1 gene. PSTPIP1 has been shown to interact…
- PTPN4 Tyrosine-protein phosphatase non-receptor type 4 is an enzyme that in humans is encoded by the PTPN4 gene. The protein encoded by this gene is a member…
- PTPRR Protein tyrosine phosphatase receptor-type R is an enzyme that in humans is encoded by the PTPRR gene. The protein encoded by this gene is a member of…