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Everything about MERTK
Protein-coding gene in humans
Proto-oncogene tyrosine-protein kinase MER is an enzyme that in humans is encoded by the MERTK gene. Wikipedia →
🧭 Start here: a 6-step reading path
- Read the overview: MERTKA 5-minute orientation
- Skim a recent paper: MerTK-mediated efferocytosis promotes immune tolerance and tumor progression in osteosarcoma through enhancing M2 polarization and PD-L1 expressionInfluential work since 2022
- Pick up a classic book: Chopin Mertke NocturnesThe most-reprinted book on the subject
- Read the landmark paper: Astrocytes mediate synapse elimination through MEGF10 and MERTK pathwaysCited 1,368 times
- Go sideways: TYRO3A closely related topic
- Go sideways: GAS6A closely related topic
📖 Definitions
No dictionary entry for this exact phrase.
🗂️ The subject at a glance
🏆 Landmark papers (most cited)
Astrocytes mediate synapse elimination through MEGF10 and MERTK pathways
Proliferating SPP1/MERTK-expressing macrophages in idiopathic pulmonary fibrosis
Mutation of the receptor tyrosine kinase gene Mertk in the retinal dystrophic RCS rat
Efficient Clearance of Early Apoptotic Cells by Human Macrophages Requires M2c Polarization and MerTK Induction
Mutations in MERTK, the human orthologue of the RCS rat retinal dystrophy gene, cause retinitis pigmentosa
Targeting Tyro3, Axl and MerTK (TAM receptors): implications for macrophages in the tumor microenvironment
Blockade of the Phagocytic Receptor MerTK on Tumor-Associated Macrophages Enhances P2X7R-Dependent STING Activation by Tumor-Derived cGAMP
Macrophages and Dendritic Cells Use Different Axl/Mertk/Tyro3 Receptors in Clearance of Apoptotic Cells
🆕 Influential since 2022
MerTK-mediated efferocytosis promotes immune tolerance and tumor progression in osteosarcoma through enhancing M2 polarization and PD-L1 expression
Trained immunity of alveolar macrophages enhances injury resolution via KLF4-MERTK-mediated efferocytosis
NOX2 inhibition stabilizes vulnerable plaques by enhancing macrophage efferocytosis via MertK/PI3K/AKT pathway
Pentoxifylline alleviates ischemic white matter injury through up-regulating Mertk-mediated myelin clearance
Stress induces behavioral abnormalities by increasing expression of phagocytic receptor MERTK in astrocytes to promote synapse phagocytosis
📚 Books worth reading
Chopin Mertke NocturnesFrederic Chopin · 1985
Ranked by number of editions on Open Library, a rough measure of how lasting a book is.
🔗 Related topics
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