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Everything about ROR2
Protein
Tyrosine-protein kinase transmembrane receptor ROR2, also known as neurotrophic tyrosine kinase, receptor-related 2, is a protein that in humans is encoded by the ROR2 gene located on position 9 of the long arm of chromosome 9. This protein is responsible for aspects of bone and cartilage growth. It is involved in Robinow syndrome and autosomal dominant brachydactyly type B. ROR2 is a member of the receptor tyrosine kinase-like orphan receptor (ROR) family. Wikipedia →
🧭 Start here: a 6-step reading path
- Read the overview: ROR2A 5-minute orientation
- Skim a recent paper: Cytoneme-mediated transport of active Wnt5b–Ror2 complexes in zebrafishInfluential work since 2022
- Pick up a classic book: Great Lives from HistoryThe most-reprinted book on the subject
- Read the landmark paper: Ror2 signaling regulates Golgi structure and transport through IFT20 for tumor invasivenessCited 12,327 times
- Go sideways: Ephrin B1A closely related topic
- Go sideways: ROR1A closely related topic
📖 Definitions
No dictionary entry for this exact phrase.
🗂️ The subject at a glance
🏆 Landmark papers (most cited)
Ror2 signaling regulates Golgi structure and transport through IFT20 for tumor invasiveness
The receptor tyrosine kinase Ror2 is involved in non‐canonical Wnt5a/JNK signalling pathway
Wnt Signaling Gradients Establish Planar Cell Polarity by Inducing Vangl2 Phosphorylation through Ror2
Wnt5a-Ror2 signaling between osteoblast-lineage cells and osteoclast precursors enhances osteoclastogenesis
Recessive Robinow syndrome, allelic to dominant brachydactyly type B, is caused by mutation of ROR2
Wnt-5A/Ror2 Regulate Expression of XPAPC through an Alternative Noncanonical Signaling Pathway
Mutation of the gene encoding the ROR2 tyrosine kinase causes autosomal recessive Robinow syndrome
Hypoxia Induces Phenotypic Plasticity and Therapy Resistance in Melanoma via the Tyrosine Kinase Receptors ROR1 and ROR2
🆕 Influential since 2022
Cytoneme-mediated transport of active Wnt5b–Ror2 complexes in zebrafish
WNT5a Signaling through ROR2 Activates the Hippo Pathway to Suppress YAP1 Activity and Tumor Growth
Roles of Wnt Signaling Pathway and ROR2 Receptor in Embryonic Development: An Update Review Article
Cancer-associated fibroblasts influence Wnt/PCP signaling in gastric cancer cells by cytoneme-based dissemination of ROR2
ROR2 Regulates Cellular Plasticity in Pancreatic Neoplasia and Adenocarcinoma
📚 Books worth reading
Great Lives from HistoryFrank N. Magill · 1987- 📕Risk finance and asset pricingCharles S. Tapiero · 2010
Data structures & algorithms in JavaRobert Lafore · 2003- 📕Agricultural Research IndexJ Burkett
Growth factors in developmentCarmen Birchmeier · 2011- 📕ROR2 Is Epigenetically Inactivated in the Early Stages of Colorectal Neoplasia and Is Associated with Proliferation and MigrationChelyabinsk Chelyabinsk Press · 2017
- 📕Medical Research Index
- 📕The First Part of a Brief Register, Kalendar and Survey of the several Kinds, Forms of all Parliamentary VVrits : Comprising In 3. Sections, all Writs, Forms of Summons to Great Councils, Parliaments, Convocations in the Tower, from the 5th of King John till 23 Edw. 4. to all sorts of Spiritual and Temporal Lords, Great- men and the Kings Counsil The House Of Lords : With other Rare Writs, and 4. Exact Alphabetical, Chro- nological Tables : 1. Of all Abbots, Priors, Masters of Orders, Clergy-men, 2. Of all Dukes, Earls, Forreign Kings, Marquesses, Princes of Wales : 3. Of all Lay-Barons, Lords, Vicounts, Great men : 4. Of all the Kings Counsil with the several numbers of each of them, and of Bishops, summoned to every Council, Parliament, and the Years, Rolls, Dorses in every Kings reign, wherein their names are recorded. Illustrated with choice, usefull Annotations, Observations concer- ning these Writs differences, alterations, entries in the Clause Rolls : the Stiles, Titles, Additions of Patriarcha, Cardinalis, Electus, Confirmatus, Ma gister, &c. given in them to Spiritual; of Baro, Miles, Dominus, &c. to Temporal Lords; with their Baronies, Fealty, Homage, Oaths, right of Session, Judicature : The Clergies forms of Procurations; Exemption from Taxes by the LaityWilliam Prynne · 1659
Ranked by number of editions on Open Library, a rough measure of how lasting a book is.
🔗 Related topics
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- Related to receptor tyrosine kinase The related to receptor tyrosine kinase (RYK) gene encodes the protein Ryk. The protein encoded by this gene is an atypical member of the family of growth…
- PTPN7 Protein tyrosine phosphatase non-receptor type 7 is an enzyme that in humans is encoded by the PTPN7 gene. The protein encoded by this gene is a member…
- Robinow syndrome Robinow syndrome is an extremely rare genetic disorder characterized by short-limbed dwarfism, abnormalities in the head, face, and external genitalia…
- PTPN11 Tyrosine-protein phosphatase non-receptor type 11 (PTPN11) also known as protein-tyrosine phosphatase 1D (PTP-1D), Src homology region 2 domain-containing…
- Collagen, type XI, alpha 1 Collagen alpha-1(XI) chain is a protein that in humans is encoded by the COL11A1 gene. The COL11A1 gene encodes one of the two alpha chains of type XI…
- TXK (gene) Tyrosine-protein kinase TXK is an enzyme that in humans is encoded by the TXK gene. This enzyme functions as a (non-specific) tyrosine protein kinase.…