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Everything about Inducer
Molecule that regulates gene expression
In molecular biology, an inducer is a molecule that regulates gene expression. An inducer functions in two ways; namely:By disabling repressors. The gene is expressed because an inducer binds to the repressor. The binding of the inducer to the repressor prevents the repressor from binding to the operator. RNA polymerase can then begin to transcribe operon genes. By binding to activators. Activators generally bind poorly to activator DNA sequences unless an inducer is present. Activator binds to an inducer and the complex binds to the activation sequence and activates target gene. Removing the inducer stops transcription. Wikipedia →
🧭 Start here: a 6-step reading path
- Read the overview: InducerA 5-minute orientation
- Skim a recent paper: Itaconate is a lysosomal inducer that promotes antibacterial innate immunityInfluential work since 2022
- Pick up a classic book: AirframeThe most-reprinted book on the subject
- Read the landmark paper: Cutting Edge: 1,25-Dihydroxyvitamin D3 Is a Direct Inducer of Antimicrobial Peptide Gene ExpressionCited 1,366 times
- Go sideways: RepressorA closely related topic
- Go sideways: Lac operonA closely related topic
📖 Definitions
Noun One who, or that which, induces.
Noun A molecule that starts gene expression.
🏆 Landmark papers (most cited)
Cutting Edge: 1,25-Dihydroxyvitamin D3 Is a Direct Inducer of Antimicrobial Peptide Gene Expression
A major inducer of anticarcinogenic protective enzymes from broccoli: isolation and elucidation of structure.
Activation Tagging of the Floral Inducer FT
An essential function for the nuclear receptor RORγt in the generation of fetal lymphoid tissue inducer cells
Metastatic Colonization Requires the Repression of the Epithelial-Mesenchymal Transition Inducer Prrx1
BMP-7 is an inducer of nephrogenesis, and is also required for eye development and skeletal patterning.
Jasmonate Regulates the INDUCER OF CBF EXPRESSION–C-REPEAT BINDING FACTOR/DRE BINDING FACTOR1 Cascade and Freezing Tolerance in Arabidopsis
cdc25+ functions as an inducer in the mitotic control of fission yeast
🆕 Influential since 2022
Itaconate is a lysosomal inducer that promotes antibacterial innate immunity
A MOF-Based Potent Ferroptosis Inducer for Enhanced Radiotherapy of Triple Negative Breast Cancer
Biosynthesis of copper oxide nanoparticles mediated Annona muricata as cytotoxic and apoptosis inducer factor in breast cancer cell lines
Augmenting Cancer Therapy with a Supramolecular Immunogenic Cell Death Inducer: A Lysosome-Targeted NIR-Light-Activated Ruthenium(II) Metallacycle
A cell membrane-targeting AIE photosensitizer as a necroptosis inducer for boosting cancer theranostics
📚 Books worth reading
AirframeMichael Crichton · 1996
NutritionLori A. Smolin, Smolin · 1994
The CIDER HOUSE RULESJohn Irving · 1985
NutritionMary B. Grosvenor · 2001
Nutrition and physical degenerationWeston A. Price, Weston Andrew Price · 1938
Principles of toxicologyRobert C. James · 2000
NutritionMary B. Grosvenor, Lori A. Smolin · 2005- 📕Food Your Miracle MedicineJean Carper · 1993
Ranked by number of editions on Open Library, a rough measure of how lasting a book is.
🔗 Related topics
- Repressor In molecular genetics, a repressor is a DNA- or RNA-binding protein that inhibits the expression of one or more genes by binding to the operator or associated…
- Lac operon The lactose operon (lac operon) is an operon required for the transport and metabolism of lactose in E. coli and many other enteric bacteria. Although…
- Operon In genetics, an operon is a functioning unit of DNA containing a cluster of genes under the control of a single promoter. The genes are transcribed together…
- Regulator gene In genetics, a regulator gene, regulator, or regulatory gene is a gene involved in controlling the expression of one or more other genes. Regulatory sequences…
- L-arabinose operon The L-arabinose operon, also called the ara or araBAD operon, is an operon required for the breakdown of the five-carbon sugar L-arabinose in Escherichia…
- Gal operon The gal operon is a prokaryotic operon, which encodes enzymes necessary for galactose metabolism. Repression of gene expression for this operon works via…
- Silencer (genetics) In genetics, a silencer is a DNA sequence capable of binding transcription regulation factors, called repressors. DNA contains genes and provides the template…
- CAMP receptor protein cAMP receptor protein (CRP), also known as catabolite activator protein (CAP), is a bacterial transcription factor that regulates gene expression in response…