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Everything about Genome

All genetic material of an organism

In the fields of molecular biology and genetics, a genome is all the genetic information of an organism. It consists of nucleotide sequences of DNA. The nuclear genome includes protein-coding genes and non-coding genes, other functional regions of the genome such as regulatory sequences, and often a substantial fraction of junk DNA with no evident function. Almost all eukaryotes have mitochondria and a small mitochondrial genome. Algae and plants also contain chloroplasts with a chloroplast genome. Wikipedia →

🧭 Start here: a 6-step reading path

  1. Read the overview: GenomeA 5-minute orientation
  2. Skim a recent paper: The STRING database in 2023: protein–protein association networks and functional enrichment analyses for any sequenced genome of interestInfluential work since 2022
  3. Pick up a classic book: Advances in geneticsThe most-reprinted book on the subject
  4. Read the landmark paper: Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profilesCited 51,066 times
  5. Go sideways: Repeated sequence (DNA)A closely related topic
  6. Go sideways: Non-coding DNAA closely related topic

📖 Definitions

Noun The complete genetic information (either DNA or, in some viruses, RNA) of an organism.

🗂️ The subject at a glance

  1. Origin of the term
  2. Definition
  3. Sequencing and mapping
  4. Viral genomes
  5. Prokaryotic genomes
  6. Eukaryotic genomes
  7. Genome size
  8. Genomic alterations
  9. Genome evolution
  10. In fiction

🏆 Landmark papers (most cited)

🆕 Influential since 2022

📚 Books worth reading

Ranked by number of editions on Open Library, a rough measure of how lasting a book is.

🔗 Related topics