Everything about GeneNetwork
Database and analysis software for systems genetics
GeneNetwork is a combined database and open-source bioinformatics data analysis software resource for systems genetics. This resource is used to study gene regulatory networks that link DNA sequence differences to corresponding differences in gene and protein expression and to variation in traits such as health and disease risk. Data sets in GeneNetwork are typically made up of large collections of genotypes and phenotypes from groups of individuals, including humans, strains of mice and rats, and organisms as diverse as Drosophila melanogaster, Arabidopsis thaliana, and barley. The inclusion of genotypes makes it practical to carry out web-based gene mapping to discover those regions of genomes that contribute to differences among individuals in mRNA, protein, and metabolite levels, as well as differences in cell function, anatomy, physiology, and behavior. Wikipedia →
🧭 Start here: a 6-step reading path
- Read the overview: GeneNetworkA 5-minute orientation
- Read the landmark paper: GeneNetwork: an interactive tool for reconstruction of genetic networks using microarray dataCited 50 times
- Go sideways: Expression quantitative trait lociA closely related topic
- Go sideways: Complex traitsA closely related topic
📖 Definitions
No dictionary entry for this exact phrase.
🗂️ The subject at a glance
🏆 Landmark papers (most cited)
GeneNetwork: an interactive tool for reconstruction of genetic networks using microarray data
GeneNetwork: framework for web-based genetics
Towards systems genetic analyses in barley: Integration of phenotypic, expression and genotype data into GeneNetwork
New Insights on Gene by Environmental Effects of Drugs of Abuse in Animal Models Using GeneNetwork
📚 Books worth reading
Open Library didn't respond; try again in a moment.
🔗 Related topics
- Expression quantitative trait loci An expression quantitative trait locus (eQTL) is a type of quantitative trait locus (QTL), a genomic locus (region of DNA) that is associated with phenotypic…
- Complex traits Complex traits, also known as polygenic or multigenic traits, are phenotypes determined by the interaction of multiple genetic and environmental factors…
- Quantitative trait locus A quantitative trait locus (QTL) is a genomic locus wherein sequence variation correlates with variation of a quantitative trait. QTLs are mapped by identifying…
- Molecular breeding Molecular breeding is the application of molecular biology tools, often in plant breeding and animal breeding. In the broad sense, molecular breeding can…
- Protein quantitative trait loci Protein quantitative trait loci (pQTL) are regions in the genome associated with variation in protein expression levels. Since proteins are the primary…
- Fine-mapping Fine-mapping is a set of methods in genetics used to identify the genetic variant or variants, often single-nucleotide polymorphisms (SNPs), most likely…
- Biostatistics Biostatistics (sometimes referred to as biometry), is a branch of statistics that applies statistical methods to a wide range of topics in the biological…
- Functional genomics Functional genomics is a field of molecular biology that attempts to describe gene (and protein) functions and interactions. Functional genomics make use…