Everything about Gene structure
Organisation of elements within a gene
Gene structure is the organisation of specialised sequence elements within a gene. Genes contain most of the information necessary for living cells to survive and reproduce. In most organisms, genes are made of DNA, where the particular DNA sequence determines the function of the gene. A gene is transcribed (copied) from DNA into RNA, which can either be non-coding RNA (ncRNA) with a direct function, or an intermediate messenger RNA (mRNA) that is then translated into protein. Each of these steps is controlled by specific sequence elements, or regions, within the gene. Every gene, therefore, requires multiple sequence elements to be functional. This includes the sequence that actually encodes the functional protein or ncRNA, as well as multiple regulatory sequence regions. These regions may be as short as a few base pairs, up to many thousands of base pairs long. Wikipedia →
🧭 Start here: a 6-step reading path
- Read the overview: Gene structureA 5-minute orientation
- Skim a recent paper: CTCF shapes chromatin structure and gene expression in health and diseaseInfluential work since 2022
- Pick up a classic book: Molecular biology of the geneThe most-reprinted book on the subject
- Read the landmark paper: General atomic and molecular electronic structure systemCited 19,290 times
- Go sideways: Silencer (genetics)A closely related topic
- Go sideways: OperonA closely related topic
📖 Definitions
No dictionary entry for this exact phrase.
🗂️ The subject at a glance
🏆 Landmark papers (most cited)
General atomic and molecular electronic structure system
Rotavirus gene structure and function
Rotavirus gene structure and function.
Prediction of gene structure
ON THE COLINEARITY OF GENE STRUCTURE AND PROTEIN STRUCTURE
Chromatin structure and gene expression.
Structure of the incompatibility gene
Structure of Human Angiotensinogen Gene
🆕 Influential since 2022
CTCF shapes chromatin structure and gene expression in health and disease
An Upstream G-Quadruplex DNA Structure Can Stimulate Gene Transcription
NSRGRN: a network structure refinement method for gene regulatory network inference
Contributions of 3D chromatin structure to cell-type-specific gene regulation
Gene Structure-Based Homology Search Identifies Highly Divergent Putative Effector Gene Family
📚 Books worth reading
Molecular biology of the geneJames D. Watson, Nancy H. Hopkins · 1965
Molecular biologyBurton E. Tropp · 2005
GenesBenjamin Lewin · 1983
Embryos, genes, and birth defectsPatrizia Ferretti · 2006
Nuclear dynamicsNicholas J. Medvedeff · 1961
ProteomicsTimothy Palzkill · 2002
Testicular Chromosome Structure and Gene ExpressionEdward Mitchell Eddy, Michael D. Griswold · 2007
Steroid hormone receptorsNobel Symposium (57th 1983 Björkborn, Karlskoga, Sweden) · 1983
Ranked by number of editions on Open Library, a rough measure of how lasting a book is.
🔗 Related topics
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