Everything About ___
Live briefing

Everything about Gene

Sequence of DNA that determines traits in an organism

In biology, the word gene has two meanings. The Mendelian gene is a basic unit of heredity. The molecular gene is a sequence of nucleotides in DNA that is transcribed to produce RNA. There are two types of molecular genes: protein-coding genes and non-coding genes. During gene expression, DNA is first copied into RNA. RNA can be directly functional or be the intermediate template for the synthesis of a protein. Wikipedia →

🧭 Start here: a 6-step reading path

  1. Read the overview: GeneA 5-minute orientation
  2. Skim a recent paper: DAVID: a web server for functional enrichment analysis and functional annotation of gene lists (2021 update)Influential work since 2022
  3. Pick up a classic book: Blood sportThe most-reprinted book on the subject
  4. Read the landmark paper: Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT MethodCited 168,111 times
  5. Go sideways: GeneticsA closely related topic
  6. Go sideways: Non-coding DNAA closely related topic

📖 Definitions

Noun A theoretical unit of heredity of living organisms which may take several values and (in principle) predetermines a precise trait of an organism's form (phenotype), such as hair color.

Noun A segment of DNA or RNA from a cell's or an organism's genome, that may take several forms and thus parameterizes a phenomenon, such as (often) the structure of a protein.

🗂️ The subject at a glance

  1. Definitions
  2. History
  3. Molecular basis
  4. Structure and function
  5. Gene expression
  6. Inheritance
  7. Genome
  8. Genetic engineering

🏆 Landmark papers (most cited)

🆕 Influential since 2022

📚 Books worth reading

Ranked by number of editions on Open Library, a rough measure of how lasting a book is.

🔗 Related topics