Everything about Functional element SNPs database
The Functional Element SNPs Database (FESD) is a biological database of single nucleotide polymorphisms in molecular biology. The database is a tool designed to organize functional elements into categories in human gene regions and to output their sequences needed for genotyping experiments as well as provide a set of SNPs that lie within each region. The database defines functional elements into ten types: promoter regions, CpG islands, 5' untranslated regions (5'-UTRs), translation start sites, splice sites, coding exons, introns, translation stop sites, polyadenylation signals, and 3' UTRs. People may reference this database for haplotype information or obtain a flanking sequence for genotyping. This may help in finding mutations that contribute to common and polygenic diseases. Researchers can manually choose a group of SNPs of special interest for certain functional elements along with their corresponding sequences. The database combines information from sources such as HapMap, UCSC GoldenPath, dbSNP, OMIM, and TRANSFAC. Users can obtain information about tag SNPs and simulate LD blocks for each gene. FESD is still a developing database and is not widely known so was unable to find projects that used the database. Research was found using similar databases or databases that are combined in FESD's information pool. Wikipedia →
🧠Start here: a 6-step reading path
- Read the overview: Functional element SNPs databaseA 5-minute orientation
- Pick up a classic book: Principles of gene manipulation and genomicsThe most-reprinted book on the subject
- Read the landmark paper: FESD: a Functional Element SNPs Database in humanCited 22 times
- Go sideways: Single-nucleotide polymorphismA closely related topic
- Go sideways: SNP arrayA closely related topic
đź“– Definitions
No dictionary entry for this exact phrase.
🏆 Landmark papers (most cited)
đź“š Books worth reading
Principles of gene manipulation and genomicsS. B. Primrose · 2006
Ranked by number of editions on Open Library, a rough measure of how lasting a book is.
đź”— Related topics
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