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Everything about LECT2 amyloidosis
Medical condition
LECT2 Amyloidosis (ALECT2) is a form of amyloidosis caused by the LECT2 protein. It was found to be the third most common cause of amyloidosis in a set of more than 4,000 individuals studied at the Mayo Clinic; the first and second most common forms the disorder were AL amyloidosis and AA amyloidosis, respectively. Amyloidosis is a disorder in which the abnormal deposition of a protein in organs and/or tissues gradually leads to organ failure and/or tissue injury. Wikipedia →
🧭 Start here: a 6-step reading path
- Read the overview: LECT2 amyloidosisA 5-minute orientation
- Skim a recent paper: LECT2 Is a Novel Antibacterial Protein in VertebratesInfluential work since 2022
- Pick up a classic book: ἸλιάςThe most-reprinted book on the subject
- Read the landmark paper: LECT2, a Ligand for Tie1, Plays a Crucial Role in Liver FibrogenesisCited 214 times
- Go sideways: LECT2A closely related topic
- Go sideways: AmyloidosisA closely related topic
📖 Definitions
No dictionary entry for this exact phrase.
🗂️ The subject at a glance
🏆 Landmark papers (most cited)
LECT2, a Ligand for Tie1, Plays a Crucial Role in Liver Fibrogenesis
Purification and primary amino acid sequence of a novel neutrophil chemotactic factor LECT2
LECT2 Functions as a Hepatokine That Links Obesity to Skeletal Muscle Insulin Resistance
LECT2 protects mice against bacterial sepsis by activating macrophages via the CD209a receptor
Molecular cloning of human and bovine LECT2 having a neutrophil chemotactic activity and its specific expression in the liver
Leukocyte cell-derived chemotaxin 2 (LECT2)–associated amyloidosis is a frequent cause of hepatic amyloidosis in the United States
Leukocyte Chemotactic Factor 2 (LECT2)-Associated Renal Amyloidosis: A Case Series
A dipeptidyl peptidase-IV inhibitor improves hepatic steatosis and insulin resistance by AMPK-dependent and JNK-dependent inhibition of LECT2 expression
🆕 Influential since 2022
LECT2 Is a Novel Antibacterial Protein in Vertebrates
β-catenin/TCF4 inhibitors ICG-001 and LF3 alleviate BDL-induced liver fibrosis by suppressing LECT2 signaling
Differential analysis of ovarian tissue between high and low-yielded laying hens in the late laying stage and the effect of LECT2 gene on follicular granulosa cells proliferation
LECT2: A pleiotropic and promising hepatokine, from bench to bedside
LECT2 Ameliorates Blood–Retinal Barrier Impairment Secondary to Diabetes Via Activation of the Tie2/Akt/mTOR Signaling Pathway
📚 Books worth reading
ἸλιάςὍμηρος · 1505
Leaves of GrassWalt Whitman · 1855
Modern Genetic AnalysisAnthony J. F. Griffiths, William M. Gelbart · 1993
Sir William Hamilton, the Man and His Philosophy, 2 LectsJohn Veitch · 2018
Suggestions on Female EducationScott, A. J. · 2018
BiologyPearson · 2009
BioAddison Wesley Longman · 2005- 📕1649, the Scripture calendarHenry Jessey · 1649
Ranked by number of editions on Open Library, a rough measure of how lasting a book is.
🔗 Related topics
- LECT2 Leukocyte cell-derived chemotaxin-2 (LECT2) is a protein first described in 1996 as a chemotactic factor for neutrophils, i.e. it stimulated human neutrophils…
- Amyloidosis Amyloidosis is a group of diseases in which abnormal proteins, known as amyloid fibrils, build up in tissue. There are several non-specific and vague signs…
- Plasma cell dyscrasias In hematology, plasma cell dyscrasias (also termed plasma cell disorders and plasma cell proliferative diseases) are a spectrum of progressively more severe…
- AL amyloidosis Amyloid light-chain (AL) amyloidosis, also known as primary amyloidosis, is the most common form of systemic amyloidosis. The disease is caused when a…
- Monoclonal gammopathy of renal significance Monoclonal gammopathy of renal significance (MGRS) are a group of kidney disorders that present with kidney damage due to nephrotoxic monoclonal immunoglobulins…
- Dysfibrinogenemia The dysfibrinogenemias consist of three types of fibrinogen disorders in which a critical blood clotting factor, fibrinogen, circulates at normal levels…
- Light chain deposition disease Light chain deposition disease (LCDD) is a rare blood cell disease which is characterized by deposition of fragments of infection-fighting immunoglobulins…
- Cardiac amyloidosis Cardiac amyloidosis is a subcategory of amyloidosis where there is depositing of the protein amyloid in the heart muscle and sometimes other organs or…