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Everything about SNP array
Technique for detecting polymorphisms in a genome
In molecular biology, SNP array is a type of DNA microarray which is used to detect polymorphisms within a population. A single nucleotide polymorphism (SNP), a variation at a single site in DNA, is the most frequent type of variation in the genome. Around 335 million SNPs have been identified in the human genome, 15 million of which are present at frequencies of 1% or higher across different populations worldwide. Wikipedia →
🧭 Start here: a 6-step reading path
- Read the overview: SNP arrayA 5-minute orientation
- Skim a recent paper: Development and evaluation of liquid SNP array for large yellow croaker (Larimichthys crocea)Influential work since 2022
- Pick up a classic book: Gene discovery for disease modelsThe most-reprinted book on the subject
- Read the landmark paper: Development and Evaluation of a Barley 50k iSelect SNP ArrayCited 322 times
- Go sideways: Loss of heterozygosityA closely related topic
- Go sideways: Virtual karyotypeA closely related topic
📖 Definitions
No dictionary entry for this exact phrase.
🗂️ The subject at a glance
🏆 Landmark papers (most cited)
Development and Evaluation of a Barley 50k iSelect SNP Array
Genome-Wide SNP Detection, Validation, and Development of an 8K SNP Array for Apple
Design of a Bovine Low-Density SNP Array Optimized for Imputation
Molecular karyotyping using an SNP array for genomewide genotyping
How array design creates SNP ascertainment bias
Allele-Specific Amplification in Cancer Revealed by SNP Array Analysis
SNP array analysis in hematologic malignancies: avoiding false discoveries
Immunochip SNP array identifies novel genetic variants conferring susceptibility to candidaemia
🆕 Influential since 2022
Development and evaluation of liquid SNP array for large yellow croaker (Larimichthys crocea)
Development of a next generation SNP genotyping array for wheat
GenoBaits Soy40K: a highly flexible and low-cost SNP array for soybean studies
Comparison of Genotype Imputation for SNP Array and Low-Coverage Whole-Genome Sequencing Data
Development of a High-Density 665 K SNP Array for Rainbow Trout Genome-Wide Genotyping
📚 Books worth reading
Gene discovery for disease modelsWeikuan Gu · 2011
Principles of gene manipulation and genomicsS. B. Primrose · 2006
Bioinformatics methods in clinical researchRune Matthiesen · 2010
Genomic structural variantsLars Feuk · 2012
Forensic DNA typing protocolsAngel Carracedo · 2005
Disease gene identificationJohanna K. DiStefano · 2011- 📕DNA fingerprinting, sequencing, and chipsKresten Ovesen · 2009
DNA electrophoresis protocols for forensic geneticsAlonso, Antonio · 2012
Ranked by number of editions on Open Library, a rough measure of how lasting a book is.
🔗 Related topics
- Loss of heterozygosity In genetics, loss of heterozygosity (LOH) is a type of genetic abnormality in diploid organisms in which one copy of an entire gene and its surrounding…
- Virtual karyotype In genetics, virtual karyotype is the digital information reflecting a karyotype, resulting from the analysis of short sequences of DNA from specific loci…
- Single-nucleotide polymorphism In genetics and bioinformatics, a single-nucleotide polymorphism (SNP /snɪp/; plural SNPs /snɪps/) is a germline substitution of a single nucleotide at…
- Gene polymorphism A gene is said to be polymorphic if more than one allele occupies that gene's locus within a population. In addition to having more than one allele at…
- Ancestry-informative marker In population genetics, an ancestry-informative marker (AIM) is a single-nucleotide polymorphism that exhibits substantially different frequencies between…
- Molecular Inversion Probe Molecular Inversion Probe (MIP) belongs to the class of Capture by Circularization molecular techniques for performing genomic partitioning, a process…
- Disease gene identification Disease gene identification is a process by which scientists identify the mutant genotypes responsible for an inherited genetic disorder. Mutations in…
- SNP genotyping SNP genotyping is the measurement of genetic variations of single nucleotide polymorphisms (SNPs) between members of a species. It is a form of genotyping…