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Everything about Tsix
Non-coding RNA in the species Homo sapiens
Tsix is a non-coding RNA gene that is antisense to the Xist RNA. Tsix binds Xist during X chromosome inactivation. The name Tsix comes from the reverse of Xist, which stands for X-inactive specific transcript. Wikipedia →
🧭 Start here: a 6-step reading path
- Read the overview: TsixA 5-minute orientation
- Skim a recent paper: Establishing Reference Values in Healthy Participants for the Cardiac Troponin T High-Sensitivity Gen 6 Assay: REF-TSIX Global Reference StudyInfluential work since 2022
- Pick up a classic book: T-6The most-reprinted book on the subject
- Read the landmark paper: Tsix, a gene antisense to Xist at the X-inactivation centreCited 684 times
- Go sideways: X-inactivationA closely related topic
- Go sideways: X-chromosome reactivationA closely related topic
📖 Definitions
No dictionary entry for this exact phrase.
🗂️ The subject at a glance
🏆 Landmark papers (most cited)
Tsix, a gene antisense to Xist at the X-inactivation centre
Targeted Mutagenesis of Tsix Leads to Nonrandom X Inactivation
Regulation of imprinted X-chromosome inactivation in mice by Tsix
Disruption of Imprinted X Inactivation by Parent-of-Origin Effects at Tsix
Tsix Silences Xist through Modification of Chromatin Structure
Molecular coupling of Tsix regulation and pluripotency
Antisense Transcription through the Xist Locus Mediates Tsix Function in Embryonic Stem Cells
Tsix transcription across the Xist gene alters chromatin conformation without affecting Xist transcription: implications for X-chromosome inactivation
🆕 Influential since 2022
Establishing Reference Values in Healthy Participants for the Cardiac Troponin T High-Sensitivity Gen 6 Assay: REF-TSIX Global Reference Study
Transcriptional stochasticity reveals multiple mechanisms of long non-coding RNA regulation at the Xist–Tsix locus
LncRNA TSIX aggravates spinal cord injury by regulating the PI3K/AKT pathway via the miR‐532‐3p/DDOST axis
LncRNA TSIX knockdown restores spinal cord injury repair through miR-30a/SOCS3 axis
Clinical performance of the next generation Elecsys Troponin T high-sensitivity Gen 6 assay in acute coronary syndrome (PERFORM-TSIX): study design
📚 Books worth reading
T-6Peter Charles Smith · 1995- 📕Mechanisms of Tsix-mediated repression of XistBryan Kee-Hong Sun · 2006
T-6 Texan in actionDavis, Larry · 1989- 📕Genetic and molecular analysis of X chromosome choice elements at TsixDena Elana Cohen · 2005
- 📕Gain-of-function manipulation and expression analysis of the Xist antisense gene TsixNicholas Stavropoulos · 2003
Ranked by number of editions on Open Library, a rough measure of how lasting a book is.
🔗 Related topics
- X-inactivation X-inactivation (also called Lyonization, after English geneticist Mary Lyon) is a process by which one of the copies of the X chromosome is inactivated…
- X-chromosome reactivation X chromosome reactivation (XCR) is the process by which the inactive X chromosome (the Xi) is re-activated in the cells of eutherian female mammals. Therian…
- XIST Xist (X-inactive specific transcript) is a non-coding RNA transcribed from the X chromosome of the placental mammals that acts as a major effector of the…
- Barr body A Barr body (named after discoverer Murray Barr) or X-chromatin is an inactive X chromosome. In species with XY sex-determination (including humans), females…
- Skewed X-inactivation Skewed X-chromosome inactivation (skewed X-inactivation) occurs when the X-inactivation of one X chromosome is favored over the other, leading to an uneven…
- Sex-chromosome dosage compensation Dosage compensation is the process by which organisms equalize the expression of genes between members of different biological sexes. Across species, different…
- Polycomb-group proteins Polycomb-group proteins (PcG proteins) are a family of protein complexes first discovered in fruit flies that can remodel chromatin such that epigenetic…
- Epigenetics of human development Epigenetics play an important role in animal development, including the development of human beings. Various epigenetic markers serve different roles that…