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Everything about STR analysis
Biological DNA analysis for allele repeats
Short tandem repeat (STR) analysis is a common molecular biology method used to compare allele repeats at specific loci in DNA between two or more samples. A short tandem repeat is a microsatellite with repeat units that are 2 to 7 base pairs in length, with the number of repeats varying among individuals, making STRs effective for human identification purposes. This method differs from restriction fragment length polymorphism analysis (RFLP) since STR analysis does not cut the DNA with restriction enzymes. Instead, polymerase chain reaction (PCR) is employed to discover the lengths of the short tandem repeats based on the length of the PCR product. Wikipedia →
🧭 Start here: a 6-step reading path
- Read the overview: STR analysisA 5-minute orientation
- Skim a recent paper: UCSF ChimeraX : Tools for structure building and analysisInfluential work since 2022
- Pick up a classic book: Forensic DNA AnalysisThe most-reprinted book on the subject
- Read the landmark paper: Cutoff criteria for fit indexes in covariance structure analysis: Conventional criteria versus new alternativesCited 91,680 times
- Go sideways: Y-STRA closely related topic
- Go sideways: Paternity IndexA closely related topic
📖 Definitions
No dictionary entry for this exact phrase.
🗂️ The subject at a glance
🏆 Landmark papers (most cited)
Cutoff criteria for fit indexes in covariance structure analysis: Conventional criteria versus new alternatives
OLEX2 : a complete structure solution, refinement and analysis program
The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools
Significance tests and goodness of fit in the analysis of covariance structures.
🆕 Influential since 2022
UCSF ChimeraX : Tools for structure building and analysis
Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021
Global, regional, and national burden of stroke and its risk factors, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021
The Pantheon+ Analysis: Cosmological Constraints
Global, regional, and national prevalence of, and risk factors for, chronic obstructive pulmonary disease (COPD) in 2019: a systematic review and modelling analysis
📚 Books worth reading
Forensic DNA AnalysisJ. Thomas McClintock · 2008
Forensic DNA analysisJaiprakash G. Shewale, Ray H. Liu · 2013
Canonical problems in scattering and potential theorySergey S. Vinogradov, S.S. Vinogradov · 2001
An introduction to forensic geneticsGoodwin, William Dr., William Goodwin · 2007
DNA electrophoresis protocols for forensic geneticsAlonso, Antonio · 2012
Forensic DNA typing protocolsAngel Carracedo · 2005- 📕DNA fingerprinting, sequencing, and chipsKresten Ovesen · 2009
- 📕Archaeological research at Blue Creek, BelizeThomas H. Guderjan, W. David Driver · 1995
Ranked by number of editions on Open Library, a rough measure of how lasting a book is.
🔗 Related topics
- Y-STR A Y-STR is a short tandem repeat (STR) on the Y-chromosome. Y-STRs are often used in forensics, paternity, and genealogical DNA testing. Y-STRs are taken…
- Paternity Index In paternity testing, Paternity Index (PI) is a calculated value generated for a single genetic marker or locus (chromosomal location or site of DNA sequence…
- Microsatellite A microsatellite is a tract of repetitive DNA that consists of a particular sequence of base pairs repeated a large number of times. Microsatellites occur…
- Restriction fragment length polymorphism In molecular biology, restriction fragment length polymorphism (RFLP) is a technique that exploits variations in homologous DNA sequences, known as polymorphism…
- Forensic DNA analysis Forensic DNA analysis is the determination of a DNA profile for legal and investigative purposes. DNA analysis methods have changed countless times over…
- Second Generation Multiplex Plus Second Generation Multiplex Plus (SGM Plus), is a DNA profiling system developed by Applied Biosystems. It is an updated version of Second Generation Multiplex…
- Variable number tandem repeat A variable number tandem repeat (or VNTR) is a location in a genome where a short nucleotide sequence is organized as a tandem repeat. These can be found…
- DNA profiling DNA profiling (also called DNA fingerprinting and genetic fingerprinting) is the process of determining an individual's deoxyribonucleic acid (DNA) characterist…