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Everything about Regulatory sequence
Segment of nucleic acid that affects the expression of associated genes
A regulatory sequence is a segment of a nucleic acid molecule which is capable of increasing or decreasing the expression of specific genes within an organism. Regulation of gene expression is an essential feature of all living organisms and viruses. Wikipedia →
🧭 Start here: a 6-step reading path
- Read the overview: Regulatory sequenceA 5-minute orientation
- Skim a recent paper: Predicting RNA-seq coverage from DNA sequence as a unifying model of gene regulationInfluential work since 2022
- Pick up a classic book: Regulatory RNAThe most-reprinted book on the subject
- Read the landmark paper: PlantCARE, a database of plant cis-acting regulatory elements and a portal to tools for in silico analysis of promoter sequencesCited 7,446 times
- Go sideways: Transcriptional regulationA closely related topic
- Go sideways: Transcription (biology)A closely related topic
📖 Definitions
No dictionary entry for this exact phrase.
🗂️ The subject at a glance
🏆 Landmark papers (most cited)
PlantCARE, a database of plant cis-acting regulatory elements and a portal to tools for in silico analysis of promoter sequences
Enhanced Regulatory Sequence Prediction Using Gapped k-mer Features
Predicting expression patterns from regulatory sequence in Drosophila segmentation
Regulatory Sequence Analysis Tools
RSAT 2015: Regulatory Sequence Analysis Tools
RSAT: regulatory sequence analysis tools
Cross-species regulatory sequence activity prediction
Sequence determinants of human gene regulatory elements
🆕 Influential since 2022
Predicting RNA-seq coverage from DNA sequence as a unifying model of gene regulation
A sequence-based global map of regulatory activity for deciphering human genetics
RSAT 2022: regulatory sequence analysis tools
A deep-time landscape of plant cis-regulatory sequence evolution
Regulatory sequence-based discovery of anti-defense genes in archaeal viruses
📚 Books worth reading
Regulatory RNAThomas Dandekar, Kishore Sharma · 1998
Regulatory Rnas In ProkaryotesAnita Marchfelder · 2011
The Regulatory GenomeEric H. Davidson · 2005
Bacterial signal transductionRyutaro Utsumi · 2008
RNA motifs and regulatory elementsP. Bengert · 2002- 📕Malignancy-specific nucleic acid sequences and viral gene expression in human mesenchymal tumorsWilliam P. Peters · 1976
- 📕Microarrays and transcription networks · 2005
Molecular microbiologyDavid H. Persing, Fred C. Tenover · 2003
Ranked by number of editions on Open Library, a rough measure of how lasting a book is.
🔗 Related topics
- Transcriptional regulation In molecular biology and genetics, transcriptional regulation is the means by which a cell regulates the conversion of DNA to RNA (transcription), thereby…
- Transcription (biology) Transcription is the process of duplicating a segment of DNA into RNA for the purpose of gene expression. Some segments of DNA are transcribed into RNA…
- Promoter (genetics) In genetics, a promoter is a sequence of DNA to which proteins bind to initiate transcription of a single RNA transcript from the DNA downstream of the…
- Regulation of gene expression Regulation of gene expression, or gene regulation, includes a wide range of mechanisms that are used by cells to increase or decrease the production of…
- Transcription factor In molecular biology, a transcription factor (TF) (or sequence-specific DNA-binding factor) is a protein that controls the rate of transcription of genetic…
- Gene expression Gene expression is the process by which the information contained within a gene is used to produce a functional gene product, such as a protein or a functional…
- Eukaryotic transcription Eukaryotic transcription is the elaborate process that eukaryotic cells use to copy genetic information stored in DNA into units of transportable complementary…
- Enhancer (genetics) In genetics, an enhancer is a short (50–1500 bp) region of DNA that can be bound by proteins (activators) to increase the likelihood that transcription…