Everything about ROM1

🧭 Start here: a 6-step reading path

1. Read the overview: ROM1A 5-minute orientation
2. Skim a recent paper: Cryo-EM structures of peripherin-2 and ROM1 suggest multiple roles in photoreceptor membrane morphogenesisInfluential work since 2022
3. Pick up a classic book: Workshop JavaScriptThe most-reprinted book on the subject
4. Read the landmark paper: Digenic Retinitis Pigmentosa Due to Mutations at the Unlinked Peripherin/ RDS and ROM1 LociCited 582 times
5. Go sideways: Peripherin 2A closely related topic
6. Go sideways: CNGB1A closely related topic

🏆 Landmark papers (most cited)

• Digenic Retinitis Pigmentosa Due to Mutations at the Unlinked Peripherin/ RDS and ROM1 Loci

  Kazuto Kajiwara, Eliot L. Berson, Thaddeus P. Dryja · 1994 · Science · 582 citations

• Mla‐ and Rom1‐mediated control of microRNA398 and chloroplast copper/zinc superoxide dismutase regulates cell death in response to the barley powdery mildew fungus

  Weihui Xu, Yan Meng, Roger P. Wise · 2013 · New Phytologist · 69 citations

• Oligomerization of Prph2 and Rom1 is essential for photoreceptor outer segment formation

  Rahel Zulliger, Shannon M Conley, Maggie L Mwoyosvi · 2018 · Human Molecular Genetics · 53 citations

• ABCA4 and ROM1: Implications for Modification of the PRPH2 -Associated Macular Dystrophy Phenotype

  Charlotte M. Poloschek, Michael Bach, Wolf A. Lagrèze · 2010 · Investigative Opthalmology & Visual Science · 52 citations

• Structural and Functional Analysis of the Native Peripherin-ROM1 Complex Isolated from Photoreceptor Cells

  Brian M. Kevany, Yaroslav Tsybovsky, Iain D.G. Campuzano · 2013 · Journal of Biological Chemistry · 49 citations

• The developmentally regulated bZIP factor ROM1 modulates transcription from lectin and storage protein genes in bean embryos

  Maw‐Shenq Chern, Hans Georg Eiben, Mauricio M. Bustos · 1996 · The Plant Journal · 47 citations

• Mutation analysis of the ROM1 gene in retinitis pigmentosa

  Roger A. Bascom, Lin Liu, John R. Heckenlively · 1995 · Human Molecular Genetics · 43 citations

• Plasmodium Protease ROM1 Is Important for Proper Formation of the Parasitophorous Vacuole

  Iset Medina Vera, Wandy L. Beatty, Photini Sinnis · 2011 · PLoS Pathogens · 38 citations

🆕 Influential since 2022

• Cryo-EM structures of peripherin-2 and ROM1 suggest multiple roles in photoreceptor membrane morphogenesis

  Dounia El Mazouni, Piet Gros · 2022 · Science Advances · 33 citations

• Rare and common variants in ROM1 and PRPH2 genes trans-modify Stargardt/ABCA4 disease

  Jana Zernant, Winston Lee, Jun Wang · 2022 · PLOS Genetics · 19 citations

• ROM1 is redundant to PRPH2 as a molecular building block of photoreceptor disc rims

  Tylor R Lewis, Mustafa S Makia, Carson M Castillo · 2023 · eLife · 7 citations

• ROM1 is redundant to PRPH2 as a molecular building block of photoreceptor disc rims

  Tylor R Lewis, Mustafa S Makia, Carson M Castillo · 2023 · eLife · 3 citations

• Peripherin-2 and ROM1 Incorporate Directly Into the Rims of Enclosing Photoreceptor Discs Without Accumulating in the Nascent Disc Lamellae

  Natalia V. Klementieva, Tylor R. Lewis, Oleg Alekseev · 2025 · Investigative Ophthalmology & Visual Science · 3 citations

📚 Books worth reading

• Workshop JavaScriptStefan Mintert · 2000
• The wine seeker's guide to Livermore ValleyThomas C. Wilmer · 2010
• 📕Sefer Ḳol dodiFeinstein, David Rabbi · 1973
• Targum Neophyti 1B. Barry Levy · 1986

Ranked by number of editions on Open Library, a rough measure of how lasting a book is.

🔗 Related topics

• Peripherin 2 Peripherin-2 is a protein, that in humans is encoded by the PRPH2 gene. Peripherin-2 is found in the rod and cone cells of the retina of the eye. Defects…
• CNGB1 Cyclic nucleotide gated channel beta 1, also known as CNGB1, is a human gene encoding an ion channel protein. Cyclic nucleotide-gated ion channel GRCh38:…
• TULP1 Tubby-related protein 1 is a protein that in humans is encoded by the TULP1 gene. TULP1 is a member of a family of tubby-like genes (TULPs) that encode…
• CRB1 Crumbs homolog 1 is a protein that in humans is encoded by the CRB1 gene. This gene encodes a protein which is similar to the Drosophila crumbs protein…
• RP1 Oxygen-regulated protein 1 also known as retinitis pigmentosa 1 protein (RP1) is a protein that in humans is encoded by the RP1 gene. This gene encodes…
• PRPF31 PRP31 pre-mRNA processing factor 31 homolog (S. cerevisiae), also known as PRPF31, is a protein which in humans is encoded by the PRPF31 gene. PRPF31 is…
• RP2 (gene) Protein XRP2 is a protein that in humans is encoded by the RP2 gene. The RP2 locus has been implicated as one cause of X-linked retinitis pigmentosa. The…
• Retinitis pigmentosa GTPase regulator X-linked retinitis pigmentosa GTPase regulator is a GTPase-binding protein that in humans is encoded by the RPGR gene. The gene is located on the X-chromosome…