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Everything about Mouse Models of Human Cancer database
Database of mouse models of human cancer
The laboratory mouse has been instrumental in investigating the genetics of human disease, including cancer, for over 110 years. The laboratory mouse has physiology and genetic characteristics very similar to humans providing powerful models for investigation of the genetic characteristics of disease. Wikipedia →
🧭 Start here: a 6-step reading path
- Read the overview: Mouse Models of Human Cancer databaseA 5-minute orientation
- Skim a recent paper: Abstract 1280: Accessing PDX genomic and treatment response data using the Mouse Models of Human Cancer database (MMHCdb) cBioPortal resourceInfluential work since 2022
- Pick up a classic book: Principles of gene manipulation and genomicsThe most-reprinted book on the subject
- Read the landmark paper: The Mouse Tumor Biology Database: A Comprehensive Resource for Mouse Models of Human CancerCited 65 times
- Go sideways: Patient derived xenograftA closely related topic
- Go sideways: NSG mouseA closely related topic
📖 Definitions
No dictionary entry for this exact phrase.
🏆 Landmark papers (most cited)
The Mouse Tumor Biology Database: A Comprehensive Resource for Mouse Models of Human Cancer
Mouse Tumor Biology (MTB): a database of mouse models for human cancer
SBCDDB: Sleeping Beauty Cancer Driver Database for gene discovery in mouse models of human cancers
Web-based access to mouse models of human cancers: the Mouse Tumor Biology (MTB) Database
MetaTropismDB: a database of organ-specific metastasis induced by human cancer cell lines in mouse models
The Mouse Models of Human Cancer database (MMHCdb)
Abstract 2839: The mouse models of human cancer database (MMHCdb)
Abstract 5102: Identifying relevant mouse models of human cancer using the mouse tumor biology database (MTB)
🆕 Influential since 2022
📚 Books worth reading
Principles of gene manipulation and genomicsS. B. Primrose · 2006
Cancer bioinformaticsSylvia Nagl · 2005- 📕Tech15projects.com · 2014
Ranked by number of editions on Open Library, a rough measure of how lasting a book is.
🔗 Related topics
- Patient derived xenograft Patient derived xenografts (PDX) are models of cancer where the tissue or cells from a patient's tumor are implanted into an immunodeficient or humanized…
- NSG mouse The NSG mouse (NOD scid gamma mouse) is a brand of immunodeficient laboratory mice, developed and marketed by Jackson Laboratory, which carries the strain…
- Laboratory mouse The laboratory mouse or lab mouse is a small mammal of the order Rodentia which is bred and used for scientific research or feeders for certain pets. Laboratory…
- Humanized mouse A humanized mouse is a genetically modified mouse that has functioning human genes, cells, tissues and/or organs. Humanized mice are commonly used as small…
- Severe combined immunodeficient mice Mice with severe combined immunodeficiency (SCIDs) are often used in the research of human disease. Human immune cells are used to develop human lymphoid…
- Mouse Genome Informatics Mouse Genome Informatics (MGI) is a free, online database and bioinformatics resource hosted by The Jackson Laboratory, with funding by the National Human…
- Genetically modified mouse A genetically modified mouse, genetically engineered mouse model (GEMM) or transgenic mouse is a mouse (Mus musculus) that has had its genome altered through…
- Coisogenic strain Coisogenic strains are one type of inbred strain that differs by a mutation at a single locus and all of the other loci are identical. There are numerous…