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Everything about Humanized mouse

Mouse carrying functioning human genes, cells, etc.

A humanized mouse is a genetically modified mouse that has functioning human genes, cells, tissues and/or organs. Humanized mice are commonly used as small animal models in biological and medical research for human therapeutics. Wikipedia →

🧭 Start here: a 6-step reading path

  1. Read the overview: Humanized mouseA 5-minute orientation
  2. Skim a recent paper: Potential Applications and Perspectives of Humanized Mouse ModelsInfluential work since 2022
  3. Pick up a classic book: The VisitorThe most-reprinted book on the subject
  4. Read the landmark paper: Humanized Mouse Models of Clinical DiseaseCited 546 times
  5. Go sideways: NSG mouseA closely related topic
  6. Go sideways: Severe combined immunodeficient miceA closely related topic

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🏆 Landmark papers (most cited)

🆕 Influential since 2022

📚 Books worth reading

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