Everything about Genetic correlation
Proportion of variance that two traits share due to genetic causes
In multivariate quantitative genetics, a genetic correlation is the proportion of variance that two traits share due to genetic causes, the correlation between the genetic influences on a trait and the genetic influences on a different trait estimating the degree of pleiotropy or causal overlap. A genetic correlation of 0 implies that the genetic effects on one trait are independent of the other, while a correlation of 1 implies that all of the genetic influences on the two traits are identical. The bivariate genetic correlation can be generalized to inferring genetic latent variable factors across > 2 traits using factor analysis. Genetic correlation models were introduced into behavioral genetics in the 1970s–1980s. Wikipedia →
🧠Start here: a 6-step reading path
- Read the overview: Genetic correlationA 5-minute orientation
- Skim a recent paper: An integrated framework for local genetic correlation analysisInfluential work since 2022
- Pick up a classic book: Multivariate Statistical MethodsThe most-reprinted book on the subject
- Read the landmark paper: Correlation between Fitness and Genetic DiversityCited 2,014 times
- Go sideways: Behavioural geneticsA closely related topic
- Go sideways: Heritability of IQA closely related topic
đź“– Definitions
No dictionary entry for this exact phrase.
🗂️ The subject at a glance
🏆 Landmark papers (most cited)
Correlation between Fitness and Genetic Diversity
The Sampling Variance of the Genetic Correlation Coefficient
Transethnic Genetic-Correlation Estimates from Summary Statistics
Correlation between Genetic and Geographic Structure in Europe
Likelihood-based inference for genetic correlation coefficients
The Variance of the Genetic Correlation Coefficient
Genetic correlation between smoking behaviors and schizophrenia
Senescence and the Genetic-Correlation Hang-Up
🆕 Influential since 2022
An integrated framework for local genetic correlation analysis
Charting the Landscape of Genetic Overlap Between Mental Disorders and Related Traits Beyond Genetic Correlation
Fast estimation of genetic correlation for biobank-scale data
Shared genetic components between metabolic syndrome and schizophrenia: Genetic correlation using multipopulation data sets
Epidermolysis Bullosa—A Different Genetic Approach in Correlation with Genetic Heterogeneity
đź“š Books worth reading
Multivariate Statistical MethodsWilliam R. Atchley, Edwin H. Bryant · 1975
Ranked by number of editions on Open Library, a rough measure of how lasting a book is.
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