Everything about Entorhinal cortex
Area of the temporal lobe of the brain
The entorhinal cortex (EC) is an area of the brain's allocortex, located in the medial temporal lobe, whose functions include being a widespread network hub for memory, navigation, and the perception of time. The EC is the main interface between the hippocampus and neocortex. The EC-hippocampus system plays an important role in declarative (autobiographical/episodic/semantic) memories and in particular spatial memories including memory formation, memory consolidation, and memory optimization in sleep. The EC is also responsible for the pre-processing (familiarity) of the input signals in the reflex nictitating membrane response of classical trace conditioning; the association of impulses from the eye and the ear occurs in the entorhinal cortex. Wikipedia →
🧭 Start here: a 6-step reading path
- Read the overview: Entorhinal cortexA 5-minute orientation
- Skim a recent paper: Entorhinal cortex directs learning-related changes in CA1 representationsInfluential work since 2022
- Pick up a classic book: Connected HippocampusThe most-reprinted book on the subject
- Read the landmark paper: Microstructure of a spatial map in the entorhinal cortexCited 3,754 times
- Go sideways: Grid cellA closely related topic
- Go sideways: SubiculumA closely related topic
📖 Definitions
Noun A part of the brain which, together with the hippocampus, is important to memory functions
🗂️ The subject at a glance
🏆 Landmark papers (most cited)
Microstructure of a spatial map in the entorhinal cortex
Spatial Representation in the Entorhinal Cortex
Speed cells in the medial entorhinal cortex
Graded persistent activity in entorhinal cortex neurons
Entorhinal cortex pathology in Alzheimer's disease
Entorhinal cortex dysfunction in Alzheimer's disease
The human entorhinal cortex: A cytoarchitectonic analysis
Functional subregions of the human entorhinal cortex
🆕 Influential since 2022
Entorhinal cortex directs learning-related changes in CA1 representations
A direct lateral entorhinal cortex to hippocampal CA2 circuit conveys social information required for social memory
Microcircuits for spatial coding in the medial entorhinal cortex
Gated transformations from egocentric to allocentric reference frames involving retrosplenial cortex, entorhinal cortex, and hippocampus
Functional network topography of the medial entorhinal cortex
📚 Books worth reading
- 📕Connected HippocampusShane O'Mara, Marian Tsanov · 2015
Ranked by number of editions on Open Library, a rough measure of how lasting a book is.
🔗 Related topics
- Grid cell A grid cell is a type of neuron within the entorhinal cortex that fires at regular intervals as an animal navigates an open area, allowing it to understand…
- Subiculum The subiculum (Latin for "support") also known as the subicular complex, or subicular cortex, is the most inferior component of the hippocampal formation…
- Hippocampus The hippocampus (pl.: hippocampi), also proper, is a major component of the brain of humans and many other vertebrates. In the human brain the hippocampus…
- Perforant path In the brain, the perforant path or perforant pathway provides a connectional route from the entorhinal cortex to all fields of the hippocampal formation…
- Dentate gyrus The dentate gyrus (DG) is one of the subfields of the hippocampus, in the hippocampal formation. The hippocampal formation is located in the temporal lobe…
- Hippocampal subfields The hippocampal subfields are four subfields CA1, CA2, CA3, and CA4 that make up the structure of the hippocampus. Regions described in the hippocampus…
- Trisynaptic circuit The trisynaptic circuit or trisynaptic loop is a relay of synaptic transmission in the hippocampus. The trisynaptic circuit is a neural circuit in the…
- Theta wave Theta waves generate the theta rhythm, a neural oscillation in the brain that underlies various aspects of cognition and behavior, including learning,…