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Everything about Perforant path
In the brain, the perforant path or perforant pathway provides a connectional route from the entorhinal cortex to all fields of the hippocampal formation, including the dentate gyrus, all CA fields, and the subiculum. Wikipedia →
🧭 Start here: a 6-step reading path
- Read the overview: Perforant pathA 5-minute orientation
- Skim a recent paper: Early adversity causes sex-specific deficits in perforant pathway connectivity and contextual memory in adolescent miceInfluential work since 2022
- Pick up a classic book: Treaty Occupationay ToxicologyThe most-reprinted book on the subject
- Read the landmark paper: Long‐lasting potentiation of synaptic transmission in the dentate area of the anaesthetized rabbit following stimulation of the perforant pathCited 5,533 times
- Go sideways: Trisynaptic circuitA closely related topic
- Go sideways: Hippocampus anatomyA closely related topic
🏆 Landmark papers (most cited)
Long‐lasting potentiation of synaptic transmission in the dentate area of the anaesthetized rabbit following stimulation of the perforant path
Long‐lasting potentiation of synaptic transmission in the dentate area of the unanaesthetized rabbit following stimulation of the perforant path
The path towards a high-performance solution-processed kesterite solar cell
Glutamate as transmitter of hippocampal perforant path
Potentiation of monosynaptic EPSPs in the perforant path-dentate granule cell synapse
Perforant path transections protect hippocampal granule cells from kainate lesion
Self-sustaining status epilepticus after brief electrical stimulation of the perforant path
Quantitative analysis of synaptic potentiation during kindling of the perforant path
🆕 Influential since 2022
Early adversity causes sex-specific deficits in perforant pathway connectivity and contextual memory in adolescent mice
Quantification of perforant path fibers for early detection of Alzheimer's disease
Novel types of frequency filtering in the lateral perforant path projections to dentate gyrus
The Amyloid Precursor Protein Regulates Synaptic Transmission at Medial Perforant Path Synapses
Presenilins regulate synaptic plasticity in the perforant pathways of the hippocampus
📚 Books worth reading
Treaty Occupationay ToxicologySuelen Queiroz · 2010- 📕ConcreteJoachim Fischer · 2008
Ranked by number of editions on Open Library, a rough measure of how lasting a book is.
🔗 Related topics
- Trisynaptic circuit The trisynaptic circuit or trisynaptic loop is a relay of synaptic transmission in the hippocampus. The trisynaptic circuit is a neural circuit in the…
- Hippocampus anatomy Hippocampus anatomy describes the physical aspects and properties of the hippocampus, a neural structure in the medial temporal lobe of each cerebral hemisphere…
- Hippocampal subfields The hippocampal subfields are four subfields CA1, CA2, CA3, and CA4 that make up the structure of the hippocampus. Regions described in the hippocampus…
- Mossy fiber (hippocampus) In the hippocampus, the mossy fiber pathway consists of unmyelinated axons projecting from granule cells in the dentate gyrus that terminate on modulatory…
- Dentate gyrus The dentate gyrus (DG) is one of the subfields of the hippocampus, in the hippocampal formation. The hippocampal formation is located in the temporal lobe…
- Schaffer collateral Schaffer collaterals are axon collaterals given off by CA3 pyramidal cells in the hippocampus. These collaterals project to area CA1 of the hippocampus…
- Subiculum The subiculum (Latin for "support") also known as the subicular complex, or subicular cortex, is the most inferior component of the hippocampal formation…
- Supramammillary nucleus The supramammillary nucleus (SuM), or supramammillary area, is a thin layer of cells in the brain that lies above the mammillary bodies. It can be considered…