Live briefing
Everything about Enhancer-FACS-seq
Enhancer-FACS-seq (eFS), developed by the Bulyk lab at Brigham and Women’s Hospital and Harvard Medical School, is a highly parallel enhancer assay that aims for the identification of active, tissue-specific transcriptional enhancers, in the context of whole Drosophila melanogaster embryos. This technology replaces the use of microscopy to screen for tissue-specific enhancers with fluorescence activated cell sorting (FACS) of dissociated cells from whole embryos, combined with identification by high-throughput Illumina sequencing. Wikipedia →
🧭 Start here: a 6-step reading path
- Read the overview: Enhancer-FACS-seqA 5-minute orientation
- Skim a recent paper: STAT3 Facilitates Super Enhancer Formation to Promote Fibroblast‐To‐Myofibroblast Differentiation by the Analysis of ATAC ‐Seq, RNA ‐Seq and ChIP ‐SeqInfluential work since 2022
- Read the landmark paper: Multiple nuclear factors interact with the immunoglobulin enhancer sequencesCited 2,021 times
- Go sideways: Enhancer (genetics)A closely related topic
- Go sideways: STARR-seqA closely related topic
📖 Definitions
No dictionary entry for this exact phrase.
🗂️ The subject at a glance
🏆 Landmark papers (most cited)
Multiple nuclear factors interact with the immunoglobulin enhancer sequences
Quantitative-enhancer-FACS-seq (QeFS) reveals epistatic interactions among motifs within transcriptional enhancers in developing Drosophila tissue
🆕 Influential since 2022
📚 Books worth reading
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🔗 Related topics
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