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Everything about DUSP2
Protein-coding gene in the species Homo sapiens
Dual specificity protein phosphatase 2 is an enzyme that in humans is encoded by the DUSP2 gene. Wikipedia →
🧭 Start here: a 6-step reading path
- Read the overview: DUSP2A 5-minute orientation
- Skim a recent paper: DUSP2 recruits CSNK2A1 to suppress AKT1-mediated apoptosis resistance under hypoxic microenvironment in pancreatic cancerInfluential work since 2022
- Read the landmark paper: The phosphatase DUSP2 controls the activity of the transcription activator STAT3 and regulates TH17 differentiationCited 147 times
- Go sideways: DUSP4A closely related topic
- Go sideways: DUSP1A closely related topic
📖 Definitions
No dictionary entry for this exact phrase.
🗂️ The subject at a glance
No outline available.
🏆 Landmark papers (most cited)
The phosphatase DUSP2 controls the activity of the transcription activator STAT3 and regulates TH17 differentiation
Highly recurrent mutations of SGK1, DUSP2 and JUNB in nodular lymphocyte predominant Hodgkin lymphoma
MiR-361-3p regulates ERK1/2-induced EMT via DUSP2 mRNA degradation in pancreatic ductal adenocarcinoma
JUNB , DUSP2 , SGK1 , SOCS1 and CREBBP are frequently mutated in T-cell/histiocyte-rich large B-cell lymphoma
DUSP2 regulates extracellular vesicle‐VEGF‐C secretion and pancreatic cancer early dissemination
DNTTIP1 promotes nasopharyngeal carcinoma metastasis via recruiting HDAC1 to DUSP2 promoter and activating ERK signaling pathway
Hypoxia/HIF1α induces lapatinib resistance in ERBB2-positive breast cancer cells via regulation of DUSP2
DUSP2-mediated inhibition of tubular epithelial cell pyroptosis confers nephroprotection in acute kidney injury
🆕 Influential since 2022
DUSP2 recruits CSNK2A1 to suppress AKT1-mediated apoptosis resistance under hypoxic microenvironment in pancreatic cancer
DUSP2 affects bladder cancer prognosis by down-regulating MEK/ERK and P38 MAPK signaling pathways through PTPN7
The SKA3-DUSP2 Axis Promotes Gastric Cancer Tumorigenesis and Epithelial-Mesenchymal Transition by Activating the MAPK/ERK Pathway
DUSP2 deletion with CRISPR/Cas9 promotes Mauthner cell axonal regeneration at the early stage of zebrafish
Retinoblastoma-associated protein is important for TRIM24-mediated activation of the mTOR signaling pathway through DUSP2 action in prostate cancer
📚 Books worth reading
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🔗 Related topics
- DUSP4 Dual specificity protein phosphatase 4 is an enzyme that in humans is encoded by the DUSP4 gene. The protein encoded by this gene is a member of the dual…
- DUSP1 Dual specificity protein phosphatase 1 is an enzyme that in humans is encoded by the DUSP1 gene. The expression of DUSP1 gene is induced in human skin…
- DUSP3 Dual specificity protein phosphatase 3 is an enzyme that in humans is encoded by the DUSP3 gene. The protein encoded by this gene is a member of the dual…
- DUSP6 Dual specificity phosphatase 6 (DUSP6) is a phosphatase enzyme that is encoded by the DUSP6 gene in humans. DUSP6 is a member of the dual specificity protein…
- DUSP12 Dual specificity protein phosphatase 12 is an enzyme that in humans is encoded by the DUSP12 gene. The protein encoded by this gene is a member of the…
- MAPK1 Mitogen-activated protein kinase 1 (MAPK 1), also known as ERK2, is an enzyme that in humans is encoded by the MAPK1 gene. The protein encoded by this…
- DUSP7 Dual specificity protein phosphatase 7 is an enzyme that in humans is encoded by the DUSP7 gene. Dual-specificity phosphatases (DUSPs) constitute a large…
- DUSP5 Dual specificity protein phosphatase 5 is an enzyme that in humans is encoded by the DUSP5 gene. The protein encoded by this gene is a member of the dual…