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Everything about ARPC5
Protein-coding gene in humans
Actin-related protein 2/3 complex subunit 5 is a protein that in humans is encoded by the ARPC5 gene. Wikipedia →
🧭 Start here: a 6-step reading path
- Read the overview: ARPC5A 5-minute orientation
- Skim a recent paper: ARPC5 deficiency leads to severe early-onset systemic inflammation and mortalityInfluential work since 2022
- Read the landmark paper: Identification and characterisation of a novel human isoform of Arp2/3 complex subunit p16‐ARC/ARPC5Cited 43 times
- Go sideways: ARPC4A closely related topic
- Go sideways: ARPC3A closely related topic
📖 Definitions
No dictionary entry for this exact phrase.
🗂️ The subject at a glance
🏆 Landmark papers (most cited)
Identification and characterisation of a novel human isoform of Arp2/3 complex subunit p16‐ARC/ARPC5
ArpC5 isoforms regulate Arp2/3 complex–dependent protrusion through differential Ena/VASP positioning
Interaction between microRNAs and actin-associated protein Arpc5 regulates translational suppression during male germ cell differentiation
Rear Polarization of the Microtubule-Organizing Center in Neointimal Smooth Muscle Cells Depends on PKCα, ARPC5, and RHAMM
ARPC5 isoforms and their regulation by calcium-calmodulin-N-WASP drive distinct Arp2/3-dependent actin remodeling events in CD4 T cells
YAP facilitates melanoma migration through regulation of actin‐related protein 2/3 complex subunit 5 (ARPC5)
Cryo-EM of human Arp2/3 complexes provides structural insights into actin nucleation modulation by ARPC5 isoforms
Inherited ARPC5 mutations cause an actinopathy impairing cell motility and disrupting cytokine signaling
🆕 Influential since 2022
ARPC5 deficiency leads to severe early-onset systemic inflammation and mortality
ARPC5 is transcriptionally activated by KLF4, and promotes cell migration and invasion in prostate cancer via up-regulating ADAM17
CPEB2 enhances cell growth and angiogenesis by upregulating ARPC5 mRNA stability in multiple myeloma
NPF binding to Arp2 is allosterically linked to the release of ArpC5’s N-terminal tail and conformational changes in Arp2/3 complex
Long noncoding RNA DSCR8 promotes the proliferation of liver cancer cells and inhibits apoptosis via the miR-22-3p/ARPC5 Axis
📚 Books worth reading
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🔗 Related topics
- ARPC4 Actin-related protein 2/3 complex subunit 4 is a protein that in humans is encoded by the ARPC4 gene. This gene encodes one of seven subunits of the human…
- ARPC3 Actin-related protein 2/3 complex subunit 3 is a protein that in humans is encoded by the ARPC3 gene. This gene encodes one of seven subunits of the Arp2/3…
- ACTR2 Actin-related protein 2 is a protein that in humans is encoded by the ACTR2 gene. The specific function of ACTR2 has not yet been determined. However,…
- ARPC2 Actin-related protein 2/3 complex subunit 2 is a protein that in humans is encoded by the ARPC2 gene. This gene encodes one of seven subunits of the human…
- ACTR3 Actin-related protein 3 is a protein that in humans is encoded by the ACTR3 gene. The specific function of this gene has not yet been determined; however…
- ARPC1A Actin-related protein 2/3 complex subunit 1A is a protein that in humans is encoded by the ARPC1A gene. This gene encodes one of seven subunits of the…
- ARPC1B Actin-related protein 2/3 complex subunit 1B is a protein that in humans is encoded by the ARPC1B gene. This gene encodes one of seven subunits of the…
- Arp2/3 complex Arp2/3 complex (Actin Related Protein 2/3 complex) is a seven-subunit protein complex that plays a major role in the regulation of the actin cytoskeleton…