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Everything about VX (nerve agent)

Chemical compound and chemical warfare nerve agent

VX is an extremely toxic synthetic chemical compound in the organophosphorus class, specifically, a thiophosphonate. In the class of nerve agents, it was developed for military use in chemical warfare after translation of earlier discoveries of organophosphate toxicity in pesticide research. In its pure form, VX is an oily, relatively non-volatile liquid that is amber-like in colour. Because of its low volatility, VX persists in environments where it is dispersed. Wikipedia →

🧭 Start here: a 6-step reading path

  1. Read the overview: VX (nerve agent)A 5-minute orientation
  2. Skim a recent paper: Selective Inhibition of Na V 1.8 with VX-548 for Acute PainInfluential work since 2022
  3. Pick up a classic book: Glubb PashaThe most-reprinted book on the subject
  4. Read the landmark paper: Rescue of CF airway epithelial cell function in vitro by a CFTR potentiator, VX-770Cited 1,170 times
  5. Go sideways: SomanA closely related topic
  6. Go sideways: SarinA closely related topic

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🏆 Landmark papers (most cited)

🆕 Influential since 2022

📚 Books worth reading

Ranked by number of editions on Open Library, a rough measure of how lasting a book is.

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