Everything about VP3

🧭 Start here: a 6-step reading path

1. Read the overview: VP3A 5-minute orientation
2. Skim a recent paper: TRAF6 autophagic degradation by avibirnavirus VP3 inhibits antiviral innate immunity via blocking NFKB/NF-κB activationInfluential work since 2022
3. Pick up a classic book: Four software toolsThe most-reprinted book on the subject
4. Read the landmark paper: Independent segregation of two antigenic specificities (VP3 and VP7) involved in neutralization of rotavirus infectivity.Cited 279 times
5. Go sideways: TheoraA closely related topic
6. Go sideways: On2 TechnologiesA closely related topic

🏆 Landmark papers (most cited)

• Independent segregation of two antigenic specificities (VP3 and VP7) involved in neutralization of rotavirus infectivity.

  Y Hoshino, M M Sereno, K Midthun · 1985 · Proceedings of the National Academy of Sciences · 279 citations

• The rhesus rotavirus gene encoding protein VP3: location of amino acids involved in homologous and heterologous rotavirus neutralization and identification of a putative fusion region.

  E R Mackow, R D Shaw, S M Matsui · 1988 · Proceedings of the National Academy of Sciences · 167 citations

• Passive protection against rotavirus-induced diarrhea by monoclonal antibodies to surface proteins vp3 and vp7

  P A Offit, R D Shaw, H B Greenberg · 1986 · Journal of Virology · 166 citations

• Direct Interaction between Two Viral Proteins, the Nonstructural Protein 2CATPase and the Capsid Protein VP3, Is Required for Enterovirus Morphogenesis

  Ying Liu, Chunling Wang, Steffen Mueller · 2010 · PLoS Pathogens · 138 citations

• RGD inclusion in VP3 provides adeno-associated virus type 2 (AAV2)-based vectors with a heparan sulfate-independent cell entry mechanism

  Wenfang Shi, Jeffrey S Bartlett · 2003 · Molecular Therapy · 134 citations

• Reassortant rotaviruses containing structural proteins vp3 and vp7 from different parents induce antibodies protective against each parental serotype

  P A Offit, H F Clark, G Blavat · 1986 · Journal of Virology · 129 citations

• VP1, the Putative RNA-Dependent RNA Polymerase of Infectious Bursal Disease Virus, Forms Complexes with the Capsid Protein VP3, Leading to Efficient Encapsidation into Virus-Like Particles

  Eleuterio Lombardo, Antonio Maraver, José R. Castón · 1999 · Journal of Virology · 123 citations

• Infection immunity of piglets to either VP3 or VP7 outer capsid protein confers resistance to challenge with a virulent rotavirus bearing the corresponding antigen

  Y Hoshino, L J Saif, M M Sereno · 1988 · Journal of Virology · 113 citations

🆕 Influential since 2022

• TRAF6 autophagic degradation by avibirnavirus VP3 inhibits antiviral innate immunity via blocking NFKB/NF-κB activation

  Tingjuan Deng, Boli Hu, Xingbo Wang · 2022 · Autophagy · 90 citations

• VP3-2022: Pembrolizumab (pembro) versus placebo for early-stage non-small cell lung cancer (NSCLC) following complete resection and adjuvant chemotherapy (chemo) when indicated: Randomized, triple-blind, phase III EORTC-1416-LCG/ETOP 8-15 – PEARLS/KEYNOTE-091 study

  L. Paz-Ares, M.E.R. O'Brien, M. Mauer · 2022 · Annals of Oncology · 67 citations

• Synergetic Contributions of Viral VP1, VP3, and 3C to Activation of the AKT-AMPK-MAPK-MTOR Signaling Pathway for Seneca Valley Virus-Induced Autophagy

  Jiangwei Song, Lei Hou, Rong Quan · 2022 · Journal of Virology · 54 citations

• Production and characterization of an AAV1-VP3-only capsid: An analytical benchmark standard

  Mario Mietzsch, Weijing Liu, Ke Ma · 2023 · Molecular Therapy - Methods & Clinical Development · 30 citations

• Influencing factors on the preservation of lytic bacteriophage VP3

  Yue Xiao, Pin Huang, Zhenzhou Huang · 2022 · Biosafety and Health · 25 citations

📚 Books worth reading

• Four software toolsTim Duffy · 1986
• Computer concepts with microcomputer applicationsGary B. Shelly, Thomas J. Cashman · 1989
• Business applications software for the IBM PCLon Ingalsbe · 1986
• Application software manualMeredith Flynn · 1992
• Using software toolsLaura Saret · 1988
• 📕Using computers and application softwareLon Ingalsbe · 1989
• 101 advanced spreadsheet exercisesLloyd D. Brooks · 1990

Ranked by number of editions on Open Library, a rough measure of how lasting a book is.

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