Everything about Yangwang U7

🧭 Start here: a 6-step reading path

1. Read the overview: Yangwang U7A 5-minute orientation
2. Skim a recent paper: SMN controls neuromuscular junction integrity through U7 snRNPInfluential work since 2022
3. Pick up a classic book: HolesThe most-reprinted book on the subject
4. Read the landmark paper: Rescue of Dystrophic Muscle Through U7 snRNA-Mediated Exon SkippingCited 472 times
5. Go sideways: Yangwang U8A closely related topic
6. Go sideways: Yangwang U9A closely related topic

🏆 Landmark papers (most cited)

• Rescue of Dystrophic Muscle Through U7 snRNA-Mediated Exon Skipping

  Aurélie Goyenvalle, Adeline Vulin, Françoise Fougerousse · 2004 · Science · 472 citations

• Unique Sm core structure of U7 snRNPs: assembly by a specialized SMN complex and the role of a new component, Lsm11, in histone RNA processing

  Ramesh S. Pillai, Matthias Grimmler, Gunter Meister · 2003 · Genes & Development · 215 citations

• Coiled bodies contain U7 small nuclear RNA and associate with specific DNA sequences in interphase human cells.

  M R Frey, A G Matera · 1995 · Proceedings of the National Academy of Sciences · 209 citations

• Identification of the Human U7 snRNP as One of Several Factors Involved in the 3′ End Maturation of Histone Premessenger RNA's

  Kimberly L. Mowry, Joan A. Steitz · 1987 · Science · 175 citations

• Purified U7 snRNPs lack the Sm proteins D1 and D2 but contain Lsm10, a new 14 kDa Sm D1‐like protein

  Ramesh S. Pillai, Cindy L. Will, Reinhard Lührmann · 2001 · The EMBO Journal · 149 citations

• The special Sm core structure of the U7 snRNP: far-reaching significance of a small nuclear ribonucleoprotein

  D. Sch�mperli, R. S. Pillai · 2004 · Cellular and Molecular Life Sciences · 148 citations

• Muscle Function Recovery in Golden Retriever Muscular Dystrophy After AAV1-U7 Exon Skipping

  Adeline Vulin, Inès Barthélémy, Aurélie Goyenvalle · 2012 · Molecular Therapy · 143 citations

• cis-Acting signals involved in termination of vesicular stomatitis virus mRNA synthesis include the conserved AUAC and the U7 signal for polyadenylation

  J N Barr, S P Whelan, G W Wertz · 1997 · Journal of Virology · 142 citations

🆕 Influential since 2022

• SMN controls neuromuscular junction integrity through U7 snRNP

  Sarah Tisdale, Meaghan Van Alstyne, Christian M. Simon · 2022 · Cell Reports · 33 citations

• An engineered U7 small nuclear RNA scaffold greatly increases ADAR-mediated programmable RNA base editing

  Susan M. Byrne, Stephen M. Burleigh, Robert Fragoza · 2025 · Nature Communications · 20 citations

• Dystrophin Restoration after Adeno-Associated Virus U7–Mediated Dmd Exon Skipping Is Modulated by Muscular Exercise in the Severe D2-Mdx Duchenne Muscular Dystrophy Murine Model

  Alexandra Monceau, Dylan Moutachi, Mégane Lemaitre · 2022 · The American Journal of Pathology · 12 citations

• Employing splice-switching oligonucleotides and AAVrh74.U7 snRNA to target insulin receptor splicing and cancer hallmarks in osteosarcoma

  Safiya Khurshid, Akila S. Venkataramany, Matias Montes · 2024 · Molecular Therapy: Oncology · 6 citations

• In vitro methylation of the U7 snRNP subunits Lsm11 and SmE by the PRMT5/MEP50/pICln methylosome

  Xiao-cui Yang, Anthony Desotell, Min-Han Lin · 2023 · RNA · 5 citations

📚 Books worth reading

• HolesLouis Sachar · 1988
• The Ugly AmericanWilliam J. Lederer, Eugene Burdick · 1958
• Into the WildJon Krakauer · 1996
• Wild Bill HickokLarissa Phillips, Tracie Egan · 2003
• SacajaweaJoseph Bruchac · 2000
• Real estate finance and investmentsWilliam B. Brueggeman, Jeffrey Fisher · 1993
• Train dreamsDenis Johnson · 2006
• Intimate mattersJohn D'Emilio, Estelle B. Freedman · 1988

Ranked by number of editions on Open Library, a rough measure of how lasting a book is.

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