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Everything about Staining
Technique used to enhance visual contrast of specimens observed under a microscope
Staining is a technique used to enhance contrast in samples, generally at the microscopic level. Stains and dyes are frequently used in histology, in cytology, and in the medical fields of histopathology, hematology, and cytopathology that focus on the study and diagnoses of diseases at the microscopic level. Stains may be used to define biological tissues, cell populations, or organelles within individual cells. Wikipedia →
🧭 Start here: a 6-step reading path
- Read the overview: StainingA 5-minute orientation
- Skim a recent paper: Deep learning-enabled virtual histological staining of biological samplesInfluential work since 2022
- Pick up a classic book: Understanding moviesThe most-reprinted book on the subject
- Read the landmark paper: Improved procedures for clearing roots and staining parasitic and vesicular-arbuscular mycorrhizal fungi for rapid assessment of infectionCited 6,429 times
- Go sideways: H&E stainA closely related topic
- Go sideways: Van Gieson's stainA closely related topic
📖 Definitions
Verb present participle and gerund of stain
🏆 Landmark papers (most cited)
Improved procedures for clearing roots and staining parasitic and vesicular-arbuscular mycorrhizal fungi for rapid assessment of infection
A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry
A New Consistent Chromosomal Abnormality in Chronic Myelogenous Leukaemia identified by Quinacrine Fluorescence and Giemsa Staining
Improved silver staining of plant proteins, RNA and DNA in polyacrylamide gels
Staining of Tissue Sections for Electron Microscopy with Heavy Metals
New Giemsa method for the differential staining of sister chromatids
Silver staining of proteins in polyacrylamide gels
Improved staining of proteins in polyacrylamide gels including isoelectric focusing gels with clear background at nanogram sensitivity using Coomassie Brilliant Blue G‐250 and R‐250
🆕 Influential since 2022
Deep learning-enabled virtual histological staining of biological samples
Copper Doped Carbon Dots for Addressing Bacterial Biofilm Formation, Wound Infection, and Tooth Staining
Highly efficient adsorption and removal bio-staining dye from industrial wastewater onto mesoporous Ag-MOFs
Microplastic detection and identification by Nile red staining: Towards a semi-automated, cost- and time-effective technique
MACSima imaging cyclic staining (MICS) technology reveals combinatorial target pairs for CAR T cell treatment of solid tumors
📚 Books worth reading
Understanding moviesLouis D. Giannetti · 1972
Stained glass of the middle ages in England & FranceHugh Arnold · 1913
Biological stainsH. J. Conn · 1925
A Woman without LiesAnn Maxwell, Elizabeth Lowell · 1985
WindowsLewis Foreman Day · 1897
Made Simple SeriesGodfrey Cave · 1994
Ancient stained and painted glassF. Sydney Eden · 1913
A practical manual of medical and biological staining techniquesEdward Gurr · 1953
Ranked by number of editions on Open Library, a rough measure of how lasting a book is.
🔗 Related topics
- H&E stain Hematoxylin and eosin stain (or haematoxylin and eosin stain or hematoxylin–eosin stain; often abbreviated as H&E stain or HE stain) is one of the principal…
- Van Gieson's stain Van Gieson's stain is a histological staining technique used to differentiate between collagen and other tissue elements in microscopic sections. It is…
- Safranin Safranin (Safranin O or basic red 2) is a biological stain used in histology and cytology. Safranin is used as a counterstain in some staining protocols…
- Phosphotungstic acid-haematoxylin stain Phosphotungstic acid haematoxylin (PTAH) is a mix of haematoxylin with phosphotungstic acid, used in histology for staining. It stains some tissue in contrastin…
- Ziehl–Neelsen stain The Ziehl–Neelsen stain, also known as the acid-fast stain, is a bacteriological staining technique used in cytopathology and microbiology to identify…
- Eosin Eosin is the name of several fluorescent acidic compounds which bind to and form salts with basic, or eosinophilic, compounds like proteins containing…
- Verhoeff's stain Verhoeff's stain, also known as Verhoeff's elastic stain (VEG) or Verhoeff–Van Gieson stain (VVG), is a staining protocol used in histology, developed…
- Gimenez stain The Gimenez staining technique uses biological stains to detect and identify bacterial infections in tissue samples. Although largely superseded by techniques…