Everything about Spheroid

🧭 Start here: a 6-step reading path

1. Read the overview: SpheroidA 5-minute orientation
2. Skim a recent paper: In Vitro three-dimensional (3D) cell culture tools for spheroid and organoid modelsInfluential work since 2022
3. Pick up a classic book: Spheroidal wave functions in electromagnetic theoryThe most-reprinted book on the subject
4. Read the landmark paper: Spheroid-based drug screen: considerations and practical approachCited 1,664 times
5. Go sideways: EllipsoidA closely related topic
6. Go sideways: Earth radiusA closely related topic

🏆 Landmark papers (most cited)

• Spheroid-based drug screen: considerations and practical approach

  Juergen Friedrich, Claudia Seidel, Reinhard Ebner · 2009 · Nature Protocols · 1,664 citations

• Cell and Environment Interactions in Tumor Microregions: The Multicell Spheroid Model

  Robert M. Sutherland · 1988 · Science · 1,474 citations

• Application of spheroid models to account for aerosol particle nonsphericity in remote sensing of desert dust

  Oleg Dubovik, Alexander Sinyuk, Tatyana Lapyonok · 2006 · Journal of Geophysical Research: Atmospheres · 1,285 citations

• Spheroid Chromatin Units (ν Bodies)

  Ada L. Olins, Donald E. Olins · 1974 · Science · 1,194 citations

• Recent advances in three‐dimensional multicellular spheroid culture for biomedical research

  Ruei‐Zhen Lin, Hwan‐You Chang · 2008 · Biotechnology Journal · 1,160 citations

• 3D tumor spheroid models for in vitro therapeutic screening: a systematic approach to enhance the biological relevance of data obtained

  Michele Zanoni, Filippo Piccinini, Chiara Arienti · 2016 · Scientific Reports · 1,089 citations

• Spheroid culture as a tool for creating 3D complex tissues

  Eelco Fennema, Nicolas Rivron, Jeroen Rouwkema · 2013 · Trends in Biotechnology · 992 citations

• Advances in establishment and analysis of three-dimensional tumor spheroid-based functional assays for target validation and drug evaluation

  Maria Vinci, Sharon Gowan, Frances Boxall · 2012 · BMC Biology · 942 citations

🆕 Influential since 2022

• In Vitro three-dimensional (3D) cell culture tools for spheroid and organoid models

  Sang-Yun Lee, In-Seong Koo, Hyun Ju Hwang · 2023 · SLAS Discovery · 189 citations

• Three-Dimensional In Vitro Tumor Spheroid Models for Evaluation of Anticancer Therapy: Recent Updates

  Pallavi Nayak, Valeria Bentivoglio, Michela Varani · 2023 · Cancers · 124 citations

• Engineered biomaterials to guide spheroid formation, function, and fabrication into 3D tissue constructs

  Nikolas Di Caprio, Jason A. Burdick · 2023 · Acta Biomaterialia · 116 citations

• Strategies to capitalize on cell spheroid therapeutic potential for tissue repair and disease modeling

  Katherine H. Griffin, Shierly W. Fok, J. Kent Leach · 2022 · npj Regenerative Medicine · 108 citations

• Three-Dimensional Spheroid Culture of Human Mesenchymal Stem Cells: Offering Therapeutic Advantages and In Vitro Glimpses of the In Vivo State

  B Linju Yen, Chen-Chan Hsieh, Pei-Ju Hsu · 2023 · Stem Cells Translational Medicine · 101 citations

📚 Books worth reading

• Spheroidal wave functions in electromagnetic theoryLe-Wei Li · 2002
• 📕Spheroid Culture in Cancer Research (1991)Rolf Bjerkvig · 2017
• Spheroidal wave functionsCarson Flammer · 1957
• 📕Fonctions sphériques de legendre et fonctions sphéroïdalesLouis Robin · 1957
• Prolate Spheroidal Wave Functions of Order ZeroAndrei Osipov, Vladimir Rokhlin · 2013
• Spheroidal Wave FunctionsJ. A. Stratton, P. M. Morse · 1956
• 📕Gitterpunkte in mehrdimensionalen KugelnArnold Walfisz · 1957
• 📕Wall shear stress measurements on a prolate spheroid at zero incidence in the DNW wind tunnelHans-Peter Kreplin · 1986

Ranked by number of editions on Open Library, a rough measure of how lasting a book is.

🔗 Related topics

• Ellipsoid An ellipsoid is a surface that can be obtained from a sphere by deforming it by means of directional scalings, or more generally, of an affine transformation…
• Earth radius Earth radius (denoted as R🜨 or RE) is the distance from the center of Earth to a point on or near its surface. Approximating the figure of Earth by an…
• Latitude In geodesy and cartography, latitude is a geographic coordinate that specifies the north-south position of a point on the surface of the Earth or another…
• Earth ellipsoid An Earth ellipsoid or Earth spheroid is a mathematical figure approximating the Earth's shape and size, used as part of a reference frame for coordinates…
• Figure of the Earth In geodesy, the figure of the Earth is the size and shape used to model planet Earth. The kind of figure depends on application, including the precision…
• Maclaurin spheroid A Maclaurin spheroid is an oblate spheroid which arises when a self-gravitating fluid body of uniform density rotates with a constant angular velocity…
• Geodesics on an ellipsoid The study of geodesics on an ellipsoid arose in connection with geodesy specifically with the solution of triangulation networks. The figure of the Earth…
• Great ellipse A great ellipse is an ellipse passing through two points on a spheroid and having the same center as that of the spheroid. Equivalently, it is an ellipse…