Everything about Ser

🧭 Start here: a 6-step reading path

1. Read the overview: SerA 5-minute orientation
2. Skim a recent paper: SER-109, an Oral Microbiome Therapy for Recurrent Clostridioides difficile InfectionInfluential work since 2022
3. Pick up a classic book: Sijillāt Maḥkamat al-Quds al-SharʻīyahThe most-reprinted book on the subject
4. Read the landmark paper: Phosphorylation of Ser-129 Is the Dominant Pathological Modification of α-Synuclein in Familial and Sporadic Lewy Body DiseaseCited 1,399 times
5. Go sideways: TamA closely related topic
6. Go sideways: BBSA closely related topic

🏆 Landmark papers (most cited)

• Phosphorylation of Ser-129 Is the Dominant Pathological Modification of α-Synuclein in Familial and Sporadic Lewy Body Disease

  John P. Anderson, Donald E. Walker, Jason M. Goldstein · 2006 · Journal of Biological Chemistry · 1,399 citations

• Expression of a Constitutively Active Akt Ser/Thr Kinase in 3T3-L1 Adipocytes Stimulates Glucose Uptake and Glucose Transporter 4 Translocation

  Aimee D. Kohn, Scott A. Summers, Morris J. Birnbaum · 1996 · Journal of Biological Chemistry · 1,042 citations

• Ultradeep Human Phosphoproteome Reveals a Distinct Regulatory Nature of Tyr and Ser/Thr-Based Signaling

  Kirti Sharma, Rochelle C.J. D’Souza, Stefka Tyanova · 2014 · Cell Reports · 984 citations

• p53AIP1, a Potential Mediator of p53-Dependent Apoptosis, and Its Regulation by Ser-46-Phosphorylated p53

  Katsutoshi Oda, Hirofumi Arakawa, Tomoaki Tanaka · 2000 · Cell · 947 citations

• Phosphorylation of Nrf2 at Ser-40 by Protein Kinase C Regulates Antioxidant Response Element-mediated Transcription

  H.-C. Huang, Truyen Nguyen, Cecil B. Pickett · 2002 · Journal of Biological Chemistry · 943 citations

• par-1, a gene required for establishing polarity in C. elegans embryos, encodes a putative Ser/Thr kinase that is asymmetrically distributed

  Su Guo, Kenneth J. Kemphues · 1995 · Cell · 886 citations

• The small GTP‐binding protein Rho binds to and activates a 160 kDa Ser/Thr protein kinase homologous to myotonic dystrophy kinase.

  T. Ishizaki, M. Maekawa, K. Fujisawa · 1996 · The EMBO Journal · 769 citations

• Axin-mediated CKI phosphorylation of β-catenin at Ser 45: a molecular switch for the Wnt pathway

  Sharon Amit, Ada Hatzubai, Yaara Birman · 2002 · Genes & Development · 666 citations

🆕 Influential since 2022

• SER-109, an Oral Microbiome Therapy for Recurrent Clostridioides difficile Infection

  Paul Feuerstadt, Thomas J. Louie, Bret Lashner · 2022 · New England Journal of Medicine · 578 citations

• Safety and Tolerability of SER-109 as an Investigational Microbiome Therapeutic in Adults With Recurrent Clostridioides difficile Infection

  Matthew D. Sims, Sahil Khanna, Paul Feuerstadt · 2023 · JAMA Network Open · 84 citations

• The RNA methyltransferase METTL8 installs m3C32 in mitochondrial tRNAsThr/Ser(UCN) to optimise tRNA structure and mitochondrial translation

  Nicole Kleiber, Nicolas Lemus-Diaz, Carina Stiller · 2022 · Nature Communications · 60 citations

• SER-109: An Oral Investigational Microbiome Therapeutic for Patients with Recurrent Clostridioides difficile Infection (rCDI)

  Sahil Khanna, Matthew Sims, Thomas J. Louie · 2022 · Antibiotics · 52 citations

• Telomere-to-telomere genome assembly of bitter melon (Momordica charantia L. var. abbreviata Ser.) reveals fruit development, composition and ripening genetic characteristics

  Anzhen Fu, Yanyan Zheng, Jing Guo · 2022 · Horticulture Research · 51 citations

📚 Books worth reading

• Sijillāt Maḥkamat al-Quds al-SharʻīyahIbrāhīm Ḥusnī Ṣādiq Rabāyiʻah · 2014
• The World Without UsAlan Weisman · 2007
• SeraSera Jeh Monastery (Karnataka, India), Sheila Rock · 2003
• A Nation of ReligionsStephen Prothero · 2006
• Manual of grassesRick Darke, Mark Griffiths · 1994
• Cellular solidsLorna J. Gibson · 1988
• Promise and PerilAnna Lannstrom · 2003
• 📕Entre ser y estarRafael Marín Trechera · 2004

Ranked by number of editions on Open Library, a rough measure of how lasting a book is.

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