Live briefing
Everything about ScGET-seq
Single-cell sequencing technology
Single-cell genome and epigenome by transposases sequencing (scGET-seq) is a DNA sequencing method for profiling open and closed chromatin. In contrast to single-cell assay for transposase-accessible chromatin with sequencing (scATAC-seq), which only targets active euchromatin, scGET-seq is also capable of probing inactive heterochromatin. Wikipedia →
🧠Start here: a 6-step reading path
- Read the overview: ScGET-seqA 5-minute orientation
- Read the landmark paper: Analyzing genomic and epigenetic profiles in single cells by hybrid transposase (scGET-seq)Cited 5 times
- Go sideways: ATAC-seqA closely related topic
- Go sideways: H3K9me3A closely related topic
đź“– Definitions
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🗂️ The subject at a glance
🏆 Landmark papers (most cited)
đź“š Books worth reading
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đź”— Related topics
- ATAC-seq ATAC-seq (Assay for Transposase-Accessible Chromatin using sequencing) is a laboratory technique used in molecular biology to assess genome-wide chromatin…
- H3K9me3 H3K9me3 is an epigenetic modification to the DNA packaging protein Histone H3. It is a mark that indicates the tri-methylation at the 9th lysine residue…
- ChIL-sequencing ChIL sequencing (ChIL-seq), also known as Chromatin Integration Labeling sequencing, is a method used to analyze protein interactions with DNA. ChIL-sequencing…
- Heterochromatin protein 1 The family of heterochromatin protein 1 (HP1) ("Chromobox Homolog", CBX) consists of highly conserved proteins, which have important functions in the cell…
- H3K36me3 H3K36me3 is an epigenetic modification to the DNA packaging protein Histone H3. It is a mark that indicates the tri-methylation at the 36th lysine residue…
- Chromodomain Chromodomains are evolutionarily conserved protein domains found across a wide variety of eukaryotic species. Some chromodomain-containing genes have multiple…
- H3K36me2 H3K36me2 is an epigenetic modification to the DNA packaging protein Histone H3. It is a mark that indicates the di-methylation at the 36th lysine residue…
- Heterochromatin Heterochromatin is a tightly packed form of chromatin, which comes in multiple varieties. These varieties lie on a continuum between the two extremes of…